关于骨骼肌收缩机制假说的实验基础。
Experimental basis of the hypotheses on the mechanism of skeletal muscle contraction.
作者信息
Grazi Enrico
机构信息
Dipartimento di Biochimica e Biologia Molecolare, Università di Ferrara, Via Borsari 46, 44100 Ferrara, Italy.
出版信息
Muscles Ligaments Tendons J. 2012 Feb 15;1(3):77-84. Print 2011 Jul.
Abstract
With time clever hypotheses may be accepted as "facts" without being supported by solid experimental evidence. In our opinion this happened with muscle contraction where pure suggestions still occupy the scene and delay the progress of the research. Among these suggestions are: 1. the believe that viscosity is irrelevant in the economy of muscle contraction, 2. the concept of the drag stroke, 3. some interpretations of the significance of the Huxley-Simmons manoeuvre, 4. the definition of the load as a force/cross-section without taking into consideration the possible, divergent effects of the infinite mass x acceleration couples. Technical questions are also raised since it is apparent that measuring equipments interfere with the measure itself.
摘要
随着时间的推移，一些巧妙的假说可能在没有坚实实验证据支持的情况下被当作“事实”接受。在我们看来，肌肉收缩领域就发生了这种情况，一些纯粹的推测仍然占据主导地位，阻碍了研究的进展。这些推测包括：1. 认为粘性在肌肉收缩过程中无关紧要；2. 拖动冲程的概念；3. 对赫胥黎 - 西蒙斯操作意义的一些解释；4. 将负荷定义为力/横截面积，而没有考虑到无限多个质量×加速度组合可能产生的不同影响。由于测量设备显然会干扰测量本身，技术问题也随之出现。
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