Obstetrics and Gynecology Service, Health Consortium of Terrassa, Barcelona, Spain.
Acta Obstet Gynecol Scand. 2013 Aug;92(8):978-81. doi: 10.1111/aogs.12165. Epub 2013 Jun 6.
We investigated the efficacy of 5% lidocaine 25 mg-prilocaine 25 mg/g cream (EMLA(®) ) applied to the uterine cervix for reducing pain during diagnostic or operative hysteroscopy, using a visual analogue scale (VAS) for pain in a prospective randomized, non-blinded, controlled study in 92 successive patients. Patients were randomized to either 3 mL of EMLA cream or 3 mL of ultrasound gel (placebo), placed endocervically and exocervically, 10 min before hysteroscopy. Intensity of pain was evaluated immediately after the procedure using a 10-cm VAS. No differences were found between the two groups (p = 0.07). The number of women who wished to stop the procedure was significantly lower in the EMLA group compared with the control group (p = 0.013). We concluded that topical instillation of EMLA does not decrease pain during hysteroscopy, but does reduce a desire to abandon the procedure.
我们研究了将 5%利多卡因 25mg-25mg/g 普鲁卡因乳膏（EMLA(®)）应用于子宫颈以减轻诊断性或手术性宫腔镜检查过程中的疼痛的效果，使用视觉模拟评分法（VAS）评估 92 例连续患者的前瞻性随机、非盲、对照研究中的疼痛。患者随机分为 EMLA 乳膏 3 mL 或超声凝胶（安慰剂）3 mL，在宫腔镜检查前 10 分钟置于宫颈内和宫颈外。在手术后立即使用 10cm VAS 评估疼痛强度。两组之间没有发现差异（p = 0.07）。与对照组相比，EMLA 组希望停止手术的女性人数明显减少（p = 0.013）。我们得出结论，局部应用 EMLA 不能减轻宫腔镜检查过程中的疼痛，但可以减少放弃手术的意愿。
