Department Gastroenterology, Great Ormond Street Hospital Foundation Trust, London, WC1N 3JH, UK.
Nutrients. 2013 Jun 5;5(6):2006-18. doi: 10.3390/nu5062006.
Parenteral nutrition (PN) is a feeding mode suitable for children that do not achieve requirements via the enteral route. For this intervention to be successful, healthcare professionals require: knowledge on nutrient requirements; access to an aseptic compounding facility; and a system that ensures adequate and safe delivery of PN. Previously, it was thought that individualised PN was the "gold standard" for delivering nutrients to children; however, studies have highlighted concerns regarding inadequate delivery of nutrients, prescribing and compounding errors. We, therefore, set out to develop and implement all-in-one (AIO) paediatric PN solutions. Through a systematic approach, four AIO PN solutions were developed: birth-two months of age (Ped 1); two months-10 kg (Ped 2); 11-15 kg (Ped 3); and 16-30 kg (Ped 4). We implemented them with the help of a teaching pack, over a one month time period, and reviewed usage at six months. At that time, five children initially received standard PN without electrolyte changes; but after a few days, electrolytes needed amendments, and three required individualised PN. A change to AIO PN is feasible and safe; however, some may require electrolyte changes, and there will always be those that will require individualised PN.
肠外营养(PN)是一种适合儿童的喂养方式,适用于无法通过肠内途径满足需求的儿童。为了使这种干预成功,医疗保健专业人员需要:了解营养需求;获得无菌配制设施;以及确保 PN 充分和安全输送的系统。以前,人们认为个体化 PN 是向儿童提供营养的“金标准”;然而,研究强调了对营养素输送、处方和配制错误的担忧。因此,我们着手开发和实施全合一(AIO)儿科 PN 解决方案。通过系统的方法,开发了四种 AIO PN 解决方案:出生至两个月龄(Ped 1);两个月至 10 公斤(Ped 2);11-15 公斤(Ped 3);和 16-30 公斤(Ped 4)。我们在教学包的帮助下,在一个月的时间内实施了这些方案,并在六个月时审查了使用情况。当时,有五个儿童最初接受了没有电解质变化的标准 PN,但几天后,电解质需要调整,其中三个需要个体化 PN。AIO PN 的改变是可行且安全的;然而,有些可能需要电解质变化,而总会有那些需要个体化 PN 的儿童。