Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmacy, Shandong University, Jinan, Shandong 250012, China.
Chem Commun (Camb). 2013 Jul 18;49(56):6295-7. doi: 10.1039/c3cc42052c.
A novel fluorogenic probe for tert-butoxy radicals based on the hydrazino-naphthalimide system is reported. Interestingly, different regioisomers exhibited significantly different optical properties toward ROS, which suggested 4-hydrazinyl naphthalimide as a potential new platform for the in vitro and in cellulo detection of alkoxyl radicals.
报道了一种基于腙基-萘酰亚胺体系的叔丁氧基自由基的新型荧光探针。有趣的是，不同的区域异构体对 ROS 表现出显著不同的光学性质，这表明 4-肼基萘酰亚胺可能成为体外和细胞内检测烷氧基自由基的新平台。
