Xie Ya, Yan Liqiang, Tang Yujian, Tang Minghui, Wang Shaoyang, Bi Li, Sun Wanying, Li Jianping
College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, Guangxi, 541004, People's Republic of China.
Guangxi Key Laboratory of Electrochemical and Magnetochemical Functional Materials, Guangxi Colleges and Universities Key Laboratory of Food Safety and Detection, Guilin, Guangxi, 541004, People's Republic of China.
J Fluoresc. 2019 Mar;29(2):399-406. doi: 10.1007/s10895-019-02348-6. Epub 2019 Jan 24.
Smart and versatile salicylaldehyde Schiff's bases have been proved their excellent performances including large shocks shift, dual emission wavelengths and sensitive to environment for fluorescence analysis. Herein, a simple salicylaldehyde Schiff's base molecular (PBAS) with aggregation-induced emission (AIE) and the excited-state intramolecular proton-transfer (ESIPT) effects was constructed for detecting NH and ClO. The highly specific and sensitive response to NH was witnessed by the fast turn-on of the strong blue fluorescence and to ClO was observed by the rapid turn off of the weak green fluorescence simultaneous decomposing of the probe. The results of mass spectrum analysis showed that probe PBAS decomposed under the influence of NH whereas probe PBAS can complex with ClO and prevent effective ESIPT process. Benefiting from its high properties, this fluorescence molecular provides an effective tool for probing NH and ClO in live cells.
智能且多功能的水杨醛席夫碱已被证明具有出色的性能，包括大的斯托克斯位移、双发射波长以及对荧光分析环境敏感。在此，构建了一种具有聚集诱导发光（AIE）和激发态分子内质子转移（ESIPT）效应的简单水杨醛席夫碱分子（PBAS）用于检测NH和ClO。通过强蓝色荧光的快速开启见证了对NH的高度特异性和灵敏响应，通过弱绿色荧光的快速关闭以及探针的同时分解观察到对ClO的响应。质谱分析结果表明，探针PBAS在NH的影响下分解，而探针PBAS可与ClO络合并阻止有效的ESIPT过程。受益于其优异的性能，这种荧光分子为在活细胞中探测NH和ClO提供了一种有效的工具。
