Carreño Ana Maria, Nakajima Sílvia Rocha, Pennini Silmara N, Candido Junior Renato, Schettini Antonio Pedro Mendes
UFAM, Manaus, AM, Brazil.
An Bras Dermatol. 2013 Mar-Apr;88(2):268-71. doi: 10.1590/S0365-05962013000200017.
Malignant Melanoma is a high mortality neoplasm. The involvement of the nail apparatus is rare, with only 2 out of 3 patients seeking medical attention as the result of recent nail melanocytic lesions. This results in late diagnosis and a prognosis worse than cutaneous melanoma. We report a female, presenting with ulcerative lesions with clinical and laboratory features compatible with leishmaniasis. On return after treatment initiation a longitudinal melanonychia was observed on her first right finger. Biopsy of the nail matrix was performed. Histopathology was compatible with melanoma in situ. Longitudinal melanonychia is not a specific sign for melanoma and it is important that the dermatologist should identify the suspect lesions correctly. The incidental diagnosis of nail melanoma in situ in our case significantly impacted the patient's survival.
恶性黑色素瘤是一种死亡率很高的肿瘤。甲器受累情况罕见,每3例因近期甲黑素细胞病变就医的患者中仅有2例如此。这导致诊断延迟,且预后比皮肤黑色素瘤更差。我们报告一名女性,其出现的溃疡性病变具有与利什曼病相符的临床和实验室特征。在开始治疗后复诊时,发现她右手食指出现纵向黑甲。对甲母质进行了活检。组织病理学结果与原位黑色素瘤相符。纵向黑甲并非黑色素瘤的特异性体征,皮肤科医生正确识别可疑病变很重要。我们病例中原位甲黑色素瘤的偶然诊断对患者的生存产生了重大影响。