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Outcome of wide local excision in dermatofibrosarcoma protuberans and use of radiotherapy for margin-positive disease.

作者信息

Hamid Raashid, Hafeez Adil, Darzi Mohd A, Zaroo Inaam, Rasool Altaf, Rashid Haroon

机构信息

Department of Plastic and Reconstructive Surgery, SKIMS, Soura, Srinagar, Jammu and Kashmir, India.

出版信息

Indian Dermatol Online J. 2013 Apr;4(2):93-6. doi: 10.4103/2229-5178.110591.

DOI:10.4103/2229-5178.110591
PMID:23741663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3673400/
Abstract

PURPOSE

Wide local excision (WLE) is the preferred treatment of dermatofibrosarcoma protuberans (DFSP). The aim is to achieve negtive margins. We followed the impact of radiotherapy used postoperatively for both margin-negative and margin-positive DFSP tumors.

MATERIALS AND METHODS

Outcome of treatment of 36 patients of DFSP treated at our hospital was assessed. Thirty patients received radiotherapy postoperatively and six patients received radiotherapy alone. The maximum dimension of the lesion was 15 cm(2). Patients were followed up for varying periods of time for any recurrence.

RESULTS

10-year actuarial local control rate was determined. Local control was realized in six patients who were treated with radiotherapy alone. 30 patients were treated by radiotherapy and surgery. Out of these 30 patients, there were 6 local failures (failure rate 10%). Actuarial control rate was 82%. The failures were among patients who had positive margins.

CONCLUSION

Radiotherapy is effective, and it decreases the recurrence rate in the treatment of DFSP. It is especially helpful in margin-positive disease. This appears true for patients treated with radiotherapy alone or radiotherapy used postoperatively.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/f8a4cfacc90c/IDOJ-4-93-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/ddfe5ba4dd03/IDOJ-4-93-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/ba0471e595ab/IDOJ-4-93-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/7d59188af323/IDOJ-4-93-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/963a175389b1/IDOJ-4-93-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/cb426136389e/IDOJ-4-93-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/ec85683e0c64/IDOJ-4-93-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/447b9c1b115c/IDOJ-4-93-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/f8a4cfacc90c/IDOJ-4-93-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/ddfe5ba4dd03/IDOJ-4-93-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/ba0471e595ab/IDOJ-4-93-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/7d59188af323/IDOJ-4-93-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/963a175389b1/IDOJ-4-93-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/cb426136389e/IDOJ-4-93-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/ec85683e0c64/IDOJ-4-93-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/447b9c1b115c/IDOJ-4-93-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ffc/3673400/f8a4cfacc90c/IDOJ-4-93-g011.jpg

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本文引用的文献

1
Dermato-fibrosarcoma protuberans. A report of 39 cases.隆突性皮肤纤维肉瘤。39例报告。
AMA Arch Surg. 1951 Mar;62(3):391-411.
2
Dermatofibrosarcoma protuberans. A study of 115 cases.隆突性皮肤纤维肉瘤。115例病例研究。
Cancer. 1962 Jul-Aug;15:717-25. doi: 10.1002/1097-0142(196207/08)15:4<717::aid-cncr2820150405>3.0.co;2-2.
3
Dermatofibrosarcoma protuberans: treatment results of 35 cases.隆突性皮肤纤维肉瘤:35例治疗结果
外阴达里埃-费朗皮肤纤维肉瘤:一种罕见肿瘤的不寻常部位
Pan Afr Med J. 2019 May 22;33:46. doi: 10.11604/pamj.2019.33.46.18861. eCollection 2019.
4
Dermatofibrosarcoma Protuberans in a 9-Year-Old Child.一名9岁儿童的隆突性皮肤纤维肉瘤
Indian Dermatol Online J. 2017 May-Jun;8(3):195-197. doi: 10.4103/idoj.IDOJ_51_16.
Radiother Oncol. 2000 Nov;57(2):175-81. doi: 10.1016/s0167-8140(00)00228-0.
4
Metastatic dermatofibrosarcoma protuberans with fibrosarcomatous change in the absence of local recurrence. A case report of simultaneous occurrence with a malignant giant cell tumor of soft parts.
Cancer. 1993 Jul 15;72(2):462-8. doi: 10.1002/1097-0142(19930715)72:2<462::aid-cncr2820720223>3.0.co;2-d.
5
Dermatofibrosarcoma protuberans. Study of fifty-six cases.隆突性皮肤纤维肉瘤。56例病例研究。
Am J Surg. 1966 May;111(5):638-44. doi: 10.1016/0002-9610(66)90031-6.
6
Dermatofibrosarcoma protuberans: an analysis of 86 cases--five with metastasis.隆突性皮肤纤维肉瘤:86例分析——5例伴有转移
Ann Surg. 1967 Nov;166(5):803-16. doi: 10.1097/00000658-196711000-00011.
7
Surgical treatment of dermatofibrosarcoma protuberans.隆突性皮肤纤维肉瘤的外科治疗
Surg Gynecol Obstet. 1986 May;162(5):449-52.