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慢性创面的认识与处理进展

Updating on understanding and managing chronic wound.

机构信息

Tahoma Research, Providence, Rhode Island, USA.

出版信息

Dermatol Ther. 2013 May-Jun;26(3):236-56. doi: 10.1111/dth.12052.

DOI:10.1111/dth.12052
PMID:23742284
Abstract

The art of healing wounds is quite complex. It requires the patient's local condition in conjunction with their systemic condition to provide the most ideal wound environment. As wound care is expanding with advances in technology, we are facing a variety of different wound care products based on an assortment of bioengineered skin substances, growth factors, oxygen therapies, low frequency ultrasound and even low energy light. While these emerging evidence-based treatments prove to be promising in improving clinical outcomes and quality of life, it challenges providers to provide cost-effective treatment plans. The goal of this paper is to introduce a discussion regarding practical clinical application of various forms of advanced wound technologies in order to optimize the art of wound healing.

摘要

治愈创伤的艺术是相当复杂的。它需要结合患者的局部状况和全身状况,为其提供最理想的创伤环境。随着技术的进步,伤口护理也在不断发展,我们面临着各种各样的不同的伤口护理产品,这些产品基于各种生物工程皮肤物质、生长因子、氧疗、低频超声,甚至低能量光。虽然这些新出现的循证治疗方法在改善临床结果和生活质量方面证明是有前景的,但也给提供者带来了提供经济有效的治疗计划的挑战。本文的目的是介绍关于各种先进伤口技术的实际临床应用的讨论,以优化创伤愈合的艺术。

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Wound healing. New modalities for a new millennium.伤口愈合。新千年的新模式。
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Therapeutic strategies for enhancing angiogenesis in wound healing.
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Towards a systems approach for chronic diseases, based on health state modeling.基于健康状态建模,迈向慢性病的系统方法。
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Glu-Trp-ONa or its acylated analogue (R-Glu-Trp-ONa) administration enhances the wound healing in the model of chronic skin wounds in rabbits.给予谷氨酸-色氨酸-钠盐(Glu-Trp-ONa)或其酰化类似物(R-Glu-Trp-ONa)可促进兔慢性皮肤伤口模型的伤口愈合。
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