Center for Wound Healing and Hyperbaric Medicine, MedStar Georgetown University Hospital, Washington, DC 20007, USA.
Semin Vasc Surg. 2012 Jun;25(2):70-4. doi: 10.1053/j.semvascsurg.2012.04.008.
Biofilm is an increasingly important topic of discussion in the care of the chronic diabetic foot wound. Treatment modalities have focused on biofilm reduction or eradication through debridement techniques, topical therapies, negative pressure therapy, and ultrasound. In addition, advanced wound healing modalities, such as bioengineered alternative tissues, require optimal wound bed preparation with specific consideration of biofilm reduction before their application. Although fundamental principles of diabetic wound care still apply, critical thought must be given to biofilm before implementing a treatment plan for the closure of these complex wounds.
生物膜是慢性糖尿病足伤口护理中越来越重要的讨论话题。治疗方式侧重于通过清创技术、局部治疗、负压治疗和超声来减少或消除生物膜。此外，生物工程替代组织等先进的伤口愈合方式需要在应用前进行特定的生物膜减少准备，以获得最佳的伤口床准备。尽管糖尿病伤口护理的基本原则仍然适用，但在为这些复杂伤口制定封闭治疗方案之前，必须认真考虑生物膜问题。
