Durães Leonardo de Castro, Durães Eliana Ferreira Ribeiro, Lobato Luiz Felipe de Campos, Oliveira Paulo Gonçalves de, Sousa João Batista de
Postgraduate Program in Medical Sciences, School of Medicine, UnB, Brasilia-DF, Brazil.
Acta Cir Bras. 2013 Jun;28(6):447-52. doi: 10.1590/s0102-86502013000600008.
To investigate the correlation between bursting pressure and breaking strength on the 7th postoperative day following left colonic anastomosis in rats.
Seventy rats were randomly divided into seven groups of ten animals each. All of the animals underwent segmental resection of the left colon and end-to-end anastomosis. The animals in groups I to VI underwent surgical laparoscopies with pneumoperitoneums using carbon dioxide or helium at pressures of 5, 12 or 20 mmHg. In Group VII, open laparotomy was performed. The animals were reoperated on postoperative day 7 to measure the bursting pressure and the breaking strength of the anastomosis.
The anastomosis bursting pressure in 70 animals was 193.10±55.56 mmHg. There was no significant difference between the groups (p=0.786). The breaking strength of the anastomosis was 0.26±0.12 N. There was no significant difference between the groups (p=0.356). Pearson's correlation test showed a low correlation (r=0.231) lacking statistical significance (p=0.054).
There was no correlation between the bursting pressure and breaking strength of left colonic anastomoses in rats on the 7th postoperative day.
研究大鼠左半结肠吻合术后第7天的破裂压力与断裂强度之间的相关性。
70只大鼠随机分为7组，每组10只。所有动物均接受左半结肠节段切除及端端吻合术。第I至VI组动物采用二氧化碳或氦气在5、12或20 mmHg压力下建立气腹进行腹腔镜手术。第VII组进行开腹手术。术后第7天对动物再次手术，测量吻合口的破裂压力和断裂强度。
70只动物的吻合口破裂压力为193.10±55.56 mmHg。各组之间无显著差异（p=0.786）。吻合口的断裂强度为0.26±0.12 N。各组之间无显著差异（p=0.356）。Pearson相关性检验显示相关性较低（r=0.231），无统计学意义（p=0.054）。
大鼠左半结肠吻合术后第7天，吻合口的破裂压力与断裂强度之间无相关性。
