Gnjidić Zoja
Poliklinika za reumatske bolesti, fizikalnu medicinu i rehabilitaciju Dr. Drago Cop, Mihanovićeva 3, 10000 Zagreb.
Reumatizam. 2012;59(2):82-8.
Gout is the most prevalent form of inflammatory arthropathy, and affecting more than 2% of the population in industrialized countries. The development and expression of gout depends on three key steps:chronic hyperuricemia, the growth ofmonosodium urate crystals and interaction between this cristals and inflammatory system. Prevalence and incidence of gout have risen in recent decades. Numerous risk factors for the development of gout have been established, including hyperuricaemia, genetic factors, dietary factors, alcohol consumption, metabolic syndrome, hypertension, obesity, diuretic use and chronic renal disease.
痛风是炎症性关节病最常见的形式,在工业化国家影响着超过2%的人口。痛风的发生和表现取决于三个关键步骤:慢性高尿酸血症、尿酸单钠晶体的形成以及这些晶体与炎症系统之间的相互作用。近几十年来,痛风的患病率和发病率都有所上升。已经确定了许多痛风发病的危险因素,包括高尿酸血症、遗传因素、饮食因素、饮酒、代谢综合征、高血压、肥胖、使用利尿剂和慢性肾病。