Department of Neuropsychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust, The Barberry National Centre for Mental Health, Birmingham, UK; School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Eur J Neurol. 2013 Nov;20(11):1467-70. doi: 10.1111/ene.12207. Epub 2013 Jun 7.
Coprolalia is a complex socially inappropriate vocal tic most frequently reported in the context of Tourette syndrome (TS) and widely portrayed as a cardinal characteristic of this condition throughout popular culture. This study investigated which clinical factors may predispose some patients with TS to experience coprolalia and the impact of this symptom on quality of life.
Participants were 60 patients with TS (39 males, mean age 32.15, SD 14.1 years) of whom 50% reported mental coprolalia (urges) and 33% reported actual involuntary swearing as a tic. Relationships between the presence of coprolalia and a range of clinical variables including severity of tics, obsessive-compulsive symptoms, attention problems, anxiety, depression, premonitory urges for tics and quality of life were investigated.
The presence of urges to utter obscene language was significantly related to non-obscene socially inappropriate symptoms and self-reported tic severity. Although experiencing socially inappropriate urges in general was correlated with the presence of mental coprolalia, only the presence of more severe tics was a good indicator of outbursts of obscene vocal tics. Having coprolalia was related to significantly poorer quality of life in TS.
As outbursts of coprolalia exert a specific negative impact on quality of life clinicians should consider improvement in this symptom during evaluation of treatment efficacy.
秽语症是一种复杂的社会不适当的发声抽动，最常报告在妥瑞氏症（TS）的背景下，并在流行文化中广泛描绘为该病症的主要特征。本研究调查了哪些临床因素可能使一些 TS 患者易患秽语症，以及该症状对生活质量的影响。
参与者为 60 名 TS 患者（39 名男性，平均年龄 32.15，SD 14.1 岁），其中 50%报告存在精神性秽语症（冲动），33%报告存在实际的不自主的脏话抽动。研究了秽语症的存在与一系列临床变量之间的关系，包括抽动的严重程度、强迫症症状、注意力问题、焦虑、抑郁、抽动前冲动和生活质量。
出现说脏话的冲动与非淫秽的社会不适当症状和自我报告的抽动严重程度显著相关。虽然一般来说，经历社会不适当的冲动与存在精神性秽语症有关，但只有更严重的抽动存在才是出现淫秽发声抽动的良好指标。出现秽语症与 TS 患者的生活质量显著下降有关。
由于秽语症的爆发对生活质量有特定的负面影响，因此临床医生在评估治疗效果时应考虑改善该症状。
