A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan, Russia.
Anal Chim Acta. 2013 Jun 19;784:65-71. doi: 10.1016/j.aca.2013.04.054. Epub 2013 May 9.
The present work introduces the determination of fluoroquinolone antibiotics (FQs) in aqueous solutions through the fluorescent response of Eu(TTA)3 and [Eu(TTA)(3)1] (TTA(-) and 1 are thenoyltrifluoroacetonate and phosphine oxide derivative) complexes encapsulated into the polyelectrolyte capsules fabricated through layer-by-layer deposition of poly(sodium 4-styrenesulfonate) (PSS) and polyethyleneimine (PEI). The variation of luminescent core, polyelectrolyte deposition and concentration conditions reveals two modes of fluorescent response on FQs of diverse structure namely the sensitization and quenching of Eu(III) centered luminescence. The obtained regularities reveal the ternary complex formation and the ligand exchange occurring at the interface of polyelectrolyte coated [Eu(TTA)(3)1] based colloids as the reasons of the diverse fluorescent response of Eu(III) centered luminescence on FQs. The factors affecting the fluorescent response have been revealed, which are: the content of luminescent core, the mode of polyelectrolyte deposition, concentration and structure of FQs. The discrimination of moxifloxacin and lomefloxacin from levofloxacin, ofloxacin, difloxacin, perfloxacin through the quenching of Eu(III) luminescence in PSS-[Eu(TTA)(3)1] colloids has been revealed.
本工作通过将 Eu(TTA)3 和 [Eu(TTA)(3)1]（TTA(-)和 1 分别为三氟乙酰丙酮和膦氧化物衍生物）配合物的荧光响应引入到通过聚电解质层层沉积聚（苯乙烯磺酸钠）（PSS）和聚乙烯亚胺（PEI）制备的聚合物胶囊中来测定水溶液中的氟喹诺酮类抗生素（FQs）。发光核、聚电解质沉积和浓度条件的变化揭示了两种不同结构的 FQs 对 Eu(III) 中心发光的荧光响应模式，即敏化和猝灭。所得到的规律揭示了三元配合物的形成以及在聚合物涂层[Eu(TTA)(3)1]基于胶体的界面处发生的配体交换是导致 Eu(III) 中心发光对 FQs 的不同荧光响应的原因。已经揭示了影响荧光响应的因素，包括：发光核的含量、聚电解质沉积的模式、FQs 的浓度和结构。通过 PSS-[Eu(TTA)(3)1]胶体中 Eu(III) 发光的猝灭，揭示了莫西沙星和洛美沙星与左氧氟沙星、氧氟沙星、二氟沙星、培氟沙星的区分。
