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杜氏肌营养不良症(DMD)中的脊柱侧凸。

Scoliosis in Duchenne muscular dystrophy (DMD).

机构信息

Rancho Los Amigos National Rehabilitation Center, Downey, CA, USA.

出版信息

Neuromuscul Disord. 2013 Aug;23(8):611-7. doi: 10.1016/j.nmd.2013.05.003. Epub 2013 Jun 6.

Abstract

Scoliosis is a frequent complication in the non-ambulant patient with Duchenne muscular dystrophy (DMD). Weakness of the paraspinal muscles leads to trunk and body positional changes facilitating the development of a progressive collapsing scoliosis which inevitably interferes with comfortable sitting and may exacerbate deteriorating respiratory function. The recommended international standard of care for management of DMD includes strategies to prolong ambulation which may delay the onset of scoliosis. In the non-ambulant child there should be regular monitoring for scoliosis and, when present, surgical treatment should undertaken at an early stage. Careful multi-disciplinary pre-operative assessment and peri-operative care are essential.

摘要

脊柱侧凸是杜氏肌营养不良症(DMD)非运动患者的常见并发症。 脊柱旁肌无力导致躯干和身体姿势改变,从而促进进行性塌陷脊柱侧凸的发展,这不可避免地会影响舒适的坐姿,并可能使呼吸功能恶化。 管理 DMD 的国际推荐标准护理包括延长活动能力的策略,这可能会延迟脊柱侧凸的发生。 在非运动的儿童中,应定期监测脊柱侧凸,如有发生,应尽早进行手术治疗。 仔细的多学科术前评估和围手术期护理至关重要。

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