Institut National de la Santé et de la Recherche Médicale (INSERM U669), Maison de Solenn-Cochin, Paris, France.
Psychiatry Res. 2013 Aug 15;208(3):257-64. doi: 10.1016/j.psychres.2013.05.014. Epub 2013 Jun 6.
There is an increasing interest in the socio-affective atypicalities observed in adults with autism spectrum disorder (ASD). The aim of this study was to further explore emotional responsiveness in adults with ASD using well-validated self-reports of alexithymia and to determine whether anhedonic features are part of a broader autism phenotype (BAP). Participants comprised 38 adults with ASD, 87 parents of ASD individuals and 47 typical controls. All participants completed the Autism Spectrum Quotient (AQ), the 20-item Toronto Alexithymia Scale, and the Bermond-Vorst Alexithymia Questionnaire, as well as the Chapman Physical and Social Anhedonia Scales. The ASD group differed from controls and parents on most measures, with the exception of physical and social anhedonia, relative to parents. Parents differed from controls on social anhedonia, and a higher proportion of parents were classed as alexithymic, relative to controls. Cluster analysis revealed that some parents share more similarities with ASD participants than with controls. The results suggest that socio-affective impairments characteristic of ASD are part of the BAP.
人们对自闭症谱系障碍（ASD）成人中观察到的社会情感异常越来越感兴趣。本研究旨在使用经过充分验证的述情障碍自我报告进一步探讨 ASD 成人的情绪反应能力，并确定快感缺失特征是否是广泛自闭症表型（BAP）的一部分。参与者包括 38 名 ASD 成人、87 名 ASD 个体的父母和 47 名典型对照组。所有参与者都完成了自闭症谱系商数（AQ）、20 项多伦多述情障碍量表、Bermond-Vorst 述情障碍问卷以及查普曼身体和社交快感缺失量表。除了相对于父母的身体和社交快感缺失外，ASD 组在大多数测试中与对照组和父母不同。与对照组相比，父母在社交快感缺失方面存在差异，且相对于对照组，更多的父母被归类为述情障碍。聚类分析显示，一些父母与 ASD 参与者的相似之处多于与对照组的相似之处。结果表明，ASD 特征的社会情感障碍是 BAP 的一部分。
