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Effect of licorice flavonoid oil on cholesterol metabolism in high fat diet rats.

作者信息

Honda Kazuhisa, Saneyasu Takaoki, Hasegawa Shin, Tominaga Yuji, Yokota Shinichi, Kamisoyama Hiroshi

机构信息

Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, Kobe, Japan.

出版信息

Biosci Biotechnol Biochem. 2013;77(6):1326-8. doi: 10.1271/bbb.130104. Epub 2013 Jun 7.

DOI:10.1271/bbb.130104
PMID:23748774
Abstract

Dietary licorice fravonoid oil (LFO) significantly decreased hepatic cholesterol and plasma lipoprotein cholesterol levels in high-fat diet rats. It significantly suppressed hydroxymethylglutaryl-CoA synthase activity and increased cholesterol 7α-hydroxylase activity. The low density lipoprotein receptor mRNA level was significantly increased by LFO. These results suggest that dietary LFO improves cholesterol metabolism in obese animals.

摘要

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