Favero Giovanni, Pfiffer Tatiana, Riedlinger Wolfram F J, Chiantera Vito, Schneider Achim
Department of Gynecology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Tumori. 2013 Mar-Apr;99(2):e70-2. doi: 10.1177/030089161309900232.
The association of gastrointestinal stromal tumors (GIST) and other cancers is well known, but its synchronous occurrence with gynecological malignancies is very uncommon. Usually, the diagnosis is accidentally established. We describe a patient with GIST and concurrent ovarian cancer and discuss the clinical implications of this finding.
A 64-year-old woman with a prior diagnosis of ovarian cancer developed a second recurrence after having undergone two operations and adjuvant chemotherapy. While tumor debulking was performed, a small, nonsuspicious lesion was removed from the greater curvature of the stomach. Histology revealed a GIST.
The association of GIST and ovarian cancer is a rarity and its synchronicity may alter the oncological prognosis and therapy of the patient.
胃肠道间质瘤（GIST）与其他癌症的关联已为人熟知，但其与妇科恶性肿瘤同时发生的情况非常罕见。通常，诊断是偶然确定的。我们描述了一名患有GIST并同时患有卵巢癌的患者，并讨论了这一发现的临床意义。
一名64岁的女性，先前被诊断患有卵巢癌，在接受了两次手术和辅助化疗后出现了第二次复发。在进行肿瘤减瘤手术时，从胃大弯处切除了一个较小的、无可疑的病变。组织学检查显示为GIST。
GIST与卵巢癌的关联很罕见，其同时发生可能会改变患者的肿瘤预后和治疗方案。
