He X P, Cao X D, Shen L L, Jiang Y M
Department of Neurobiology, Faculty of Basic Medical Sciences, Shanghai Medical University.
Sheng Li Xue Bao. 1990 Apr;42(2):141-8.
The present study was undertaken to investigate the effect of electroacupuncture (EA) on electroconvulsive shock (ECS) and penicillin-induced convulsions in rats, using power spectrum analysis technique. Under quiet state, delta and theta bands were found to be predominant in the power spectrum of spontaneous EEG's with the peak of the main power in the delta band. During ECS and penicillin-induced convulsions, the power percentage of the delta band decreased, while those of alpha and beta bands increased. The bands with the peak of the main power shifted to the right, and the total power was distinctly enhanced. No marked change in background EEG activity was observed during EA stimulation. In the case of EA plus ECS or penicillin-induced convulsions, the power percentage of the delta band increased, while those of alpha and beta bands decreased. The peak of the main power returned to the delta band with a decreased total power. The compressed power spectrum array showed distinct suppression of convulsions by EA audio-visually. These results suggest that EA enables the EEG to synchronize and enhances the inhibitory process of the brain, thereby plays its anticonvulsant role.
本研究采用功率谱分析技术,探讨电针对大鼠电惊厥休克(ECS)和青霉素诱发惊厥的影响。在安静状态下,发现大鼠自发脑电图的功率谱中以δ波和θ波为主,主功率峰值在δ波频段。在ECS和青霉素诱发惊厥期间,δ波频段的功率百分比下降,而α波和β波频段的功率百分比增加。主功率峰值所在频段右移,总功率明显增强。电针刺激期间,背景脑电图活动未见明显变化。在电针加ECS或青霉素诱发惊厥的情况下,δ波频段的功率百分比增加,而α波和β波频段的功率百分比下降。主功率峰值回到δ波频段,总功率降低。压缩功率谱阵列直观地显示电针明显抑制惊厥。这些结果表明,电针可使脑电图同步化,增强大脑的抑制过程,从而发挥其抗惊厥作用。