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[心肌梗死中免疫复合物的特征]

[Characteristics of immune complexes in myocardial infarct].

作者信息

Korochkin E M, Chukaeva I I, Litvinova S N, Klebanov G I, Kreĭnina M V, Cherniak V Ia

出版信息

Sov Med. 1990(4):7-11.

PMID:2374978
Abstract

Nonspecific circulating immune complexes (CIC), different in size and stability, are detectable in the blood sera of patients with myocardial infarction; changed concentration of these complexes appears to be a reflection of the defense response of the body, aimed at homeostasis maintenance. No relationship between cardiac glycosides and CIC levels was revealed in patients with myocardial infarction. A reduction of the level of 'large' CICs by days 21-30 of the condition was observed in the patients treated with anticoagulants from the first day of the disease. A low CIC level in the acute period of the disease is a prognostically unfavorable sign in respect of the outcome of the condition.

摘要

非特异性循环免疫复合物(CIC)大小和稳定性各异,可在心肌梗死患者的血清中检测到;这些复合物浓度的变化似乎反映了机体旨在维持内环境稳定的防御反应。心肌梗死患者中未发现强心苷与CIC水平之间存在关联。从疾病第一天起接受抗凝治疗的患者,在病程第21 - 30天时观察到“大”CIC水平降低。疾病急性期CIC水平低对于病情转归而言是一个预后不良的征象。

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