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运动诱发性哮喘

Exercise-induced asthma.

作者信息

Anderson S D, Silverman M, König P, Godfrey S

出版信息

Br J Dis Chest. 1975 Jan;69(1):1-39. doi: 10.1016/0007-0971(75)90053-4.

DOI:10.1016/0007-0971(75)90053-4
PMID:237526
Abstract

A review of exercise-induced asthma is presented which describes work that has been carried out by the authors and by other investigators over recent years. The effect of exericse on lung function in asthmatic and normal subjects is compared. The influence of the type and severity of exercise on the response of the asthmatic is noted and the importance this has for interpretation of results. The effects of various drugs on exercise-induced asthma are considered in some detail. The clinical implications of the results of exercise tests in asthmatics, their relatives, and other subjects are considered in terms of the diagnosis and prognosis of asthma and its mode of inheritance. It is concluded that there is as yet no explantation for the mechanism of exercise-induced asthma, but it is a tool of potentially great value for research into the physiology and treatment of clinical asthma.

摘要

本文对运动诱发性哮喘进行了综述,描述了作者及其他研究人员近年来所开展的工作。比较了运动对哮喘患者和正常受试者肺功能的影响。注意到运动类型和强度对哮喘患者反应的影响及其对结果解读的重要性。详细探讨了各种药物对运动诱发性哮喘的作用。从哮喘的诊断、预后及其遗传方式等方面考虑了哮喘患者、其亲属及其他受试者运动试验结果的临床意义。结论是,目前尚无对运动诱发性哮喘机制的解释,但它是研究临床哮喘生理学和治疗方法的一个具有潜在巨大价值的工具。

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Exercise-induced asthma.运动诱发性哮喘
Br J Dis Chest. 1975 Jan;69(1):1-39. doi: 10.1016/0007-0971(75)90053-4.
2
Exercise-induced asthma.运动诱发性哮喘
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Exercise-induced asthma--clinical, physiological, and therapeutic implications.运动诱发性哮喘——临床、生理及治疗意义
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The use of anti-asthmatic drugs. Do they affect sports performance?抗哮喘药物的使用。它们会影响运动表现吗?
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Pharmacologic therapy for asthma: overview and historical perspective.哮喘的药物治疗:概述与历史回顾
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[Bronchial asthma induced by exercise (author's transl)].
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Suppression of exercise-induced asthma by salbutamol, theophylline, atropine, cromolyn, and placebo in a group of asthmatic children.沙丁胺醇、茶碱、阿托品、色甘酸和安慰剂对一组哮喘儿童运动诱发哮喘的抑制作用。
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Inhibition of exercise-induced asthma by different pharmacological pathways.通过不同药理途径抑制运动诱发性哮喘
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Sodium cromoglycate (cromolyn sodium): a review of its mode of action, pharmacology, therapeutic efficacy and use.色甘酸钠:其作用机制、药理学、治疗效果及应用综述
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Specificity of exercise in exercise-induced asthma.运动诱发哮喘中运动的特异性。
Br Med J. 1971 Dec 4;4(5787):577-81. doi: 10.1136/bmj.4.5787.577.

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'Indirect' challenges from science to clinical practice.科学对临床实践的“间接”挑战。
Eur Clin Respir J. 2016 Feb 22;3:31096. doi: 10.3402/ecrj.v3.31096. eCollection 2016.
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Exertional-induced bronchoconstriction: comparison between cardiopulmonary exercise test and methacholine challenging test.
运动诱发性支气管收缩:心肺运动试验与乙酰甲胆碱激发试验的比较
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Prostaglandin E2 prevents hyperosmolar-induced human mast cell activation through prostanoid receptors EP2 and EP4.前列腺素E2通过前列腺素受体EP2和EP4预防高渗诱导的人肥大细胞活化。
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Effects of exercise training on airway hyperreactivity in asthma: a systematic review and meta-analysis.运动训练对哮喘气道高反应性的影响:系统评价和荟萃分析。
Sports Med. 2013 Nov;43(11):1157-70. doi: 10.1007/s40279-013-0077-2.
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Pediatric athletic asthmatics.小儿运动性哮喘患者
Curr Allergy Asthma Rep. 2008 Nov;8(6):500-4. doi: 10.1007/s11882-008-0091-x.
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Beta2-agonists and exercise-induced asthma.β2 激动剂与运动诱发性哮喘
Clin Rev Allergy Immunol. 2006 Oct-Dec;31(2-3):163-80. doi: 10.1385/CRIAI:31:2:163.
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Long-acting beta 2-adrenoceptor agonists and exercise-induced asthma: lessons to guide us in the future.长效β2肾上腺素能受体激动剂与运动诱发性哮喘:指引我们未来的经验教训。
Paediatr Drugs. 2004;6(3):161-75. doi: 10.2165/00148581-200406030-00003.
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Methods for "indirect" challenge tests including exercise, eucapnic voluntary hyperpnea, and hypertonic aerosols.“间接”激发试验的方法,包括运动、等碳酸性自主过度通气和高渗气雾剂。
Clin Rev Allergy Immunol. 2003 Feb;24(1):27-54. doi: 10.1385/CRIAI:24:1:27.
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Formoterol delivered by Turbuhaler: in pediatric asthma.
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