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口腔黏膜下纤维化患者的精神疾病发病率:一项对照研究。

Psychiatric morbidity among patients with oral submucous fibrosis: a controlled study.

作者信息

Raja Jigna V, Rai Puja, Kumar Naveen C, Khan Mubeen, Chandrashekar H

机构信息

Department of Oral Medicine and Radiology, Dr Syamala Reddy Dental College Hospital and Research Centre, Bangalore, Karnataka, India.

出版信息

Oral Health Dent Manag. 2013 Jun;12(2):85-94.

Abstract

AIM

The study aimed to evaluate the association between oral submucous fibrosis (OSF) and psychiatric morbidity in a controlled manner.

METHODS

Matched patients were divided into three groups: Those with areca nut chewing habits with OSF (Group 1; n=50); those with areca nut chewing habits without OSF (Group 2; n=50); those without areca habits and with dental problems other than OSF (Group 3; n=50). The Mini International Neuropsychiatric Interview was used to assess psychiatric morbidity. Dependence to areca products was also assessed.

RESULTS

Sixteen (32%) Group 1 patients had psychiatric morbidity compared to one (2%) in Group 2 and two (4%) in Group 3 (P<0.001). Further, psychiatric morbidity was significantly higher among patients with advanced stages of OSF. In Groups 1 and 2, 49 (98%) and 47 (94%) patients, respectively, had dependence on areca products.

CONCLUSION

This study has suggested the association of substantial psychiatric morbidity among patients with OSF. In addition to mandatory psychiatric management of these patients, future research should be targeted at a prospective evaluation of a cause and effect relationship as well as at psychiatric interventions.

摘要

目的

本研究旨在以对照方式评估口腔黏膜下纤维化(OSF)与精神疾病发病率之间的关联。

方法

将匹配的患者分为三组:有咀嚼槟榔习惯且患有OSF的患者(第1组;n = 50);有咀嚼槟榔习惯但无OSF的患者(第2组;n = 50);无槟榔习惯且患有除OSF之外其他牙科问题的患者(第3组;n = 50)。采用《迷你国际神经精神访谈》评估精神疾病发病率。还评估了对槟榔制品的依赖情况。

结果

第1组有16名(32%)患者患有精神疾病,相比之下,第2组有1名(2%),第3组有2名(4%)(P < 0.001)。此外,OSF晚期患者的精神疾病发病率显著更高。在第1组和第2组中,分别有49名(98%)和47名(94%)患者对槟榔制品有依赖。

结论

本研究表明OSF患者中存在大量精神疾病发病情况。除了对这些患者进行必要的精神管理外,未来的研究应针对因果关系的前瞻性评估以及精神干预措施。

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