Zielhuis G A, Rach G H, van den Broek P
Department of Epidemiology, University of Nijmegen, The Netherlands.
Eur Arch Otorhinolaryngol. 1990;247(4):215-21. doi: 10.1007/BF00178987.
In order to gain an insight into the natural course of otitis media with effusion (OME), a prospective study was carried out on 1328 children out of a cohort of 1439 preschool children. These children were seen in follow-up for their OME every 3 months, at which times tympanometry was performed. The results show a fairly constant rate of improvement of about 50% every 3 months. The cumulative rate of recurrence of OME was about 50% in the study period. Two-thirds of all OME with flat tympanograms had a duration of less than 3 months. Some factors could be identified as having an effect on the natural history of OME. The season and patients' age and sex were found to be associated with the duration and the recovery rate. Risk factors for recurrences were the same as those already reported in the literature.
为深入了解分泌性中耳炎（OME）的自然病程，对1439名学龄前儿童队列中的1328名儿童进行了一项前瞻性研究。这些儿童每3个月接受一次OME随访，届时进行鼓室图检查。结果显示，每3个月的改善率相当稳定，约为50%。在研究期间，OME的累积复发率约为50%。所有鼓室图平坦的OME中，三分之二的病程少于3个月。可以确定一些因素对OME的自然病程有影响。发现季节、患者年龄和性别与病程及恢复率有关。复发的危险因素与文献中已报道的相同。
