Zhu Ya-Zhen, Li Wei-Ping, Wang Zhi-Yuan, Yang Hai-Feng, He Qing-Lian, Zhu Hong-Guang, Zheng Guang-Juan
Department of Pathology, Guangdong provincial hospital of TCM, Guangzhou University of Chinese Medicine, 111 Dade Road, Guangzhou 510120, China.
J Cardiothorac Surg. 2013 Jun 7;8:146. doi: 10.1186/1749-8090-8-146.
Glomus tumor is usually a small, benign tumor and typically occurs in the dermis or subcutis or soft tissue of the extremities and rarely in the visceral locations. Its occurrence in the main bronchus is extremely rare. The current case reported a 30-year-old woman with dyspnea on exertion and hemoptysis, she had a glomus tumor which has large size, deep location and exhibits an infiltrative margin as well as increased atypical mitotic figures. These characteristics suggest malignant behavior. However, there is little data regarding glomus tumors arising in the bronchus, the need for caution in diagnosing this case as a malignant glomus tumor must be highlighted. Therefore, the diagnosis of bronchial glomus tumor of uncertain malignant potential was favored. To the best of our knowledge, both the type and the location of this glomus tumor are extremely rare. Accumulation of more cases are needed to clarify their diagnosis and significance since there is little data regarding glomus tumors arising in the bronchus.
血管球瘤通常是一种小的良性肿瘤,典型地发生于四肢的真皮、皮下组织或软组织,很少发生在内脏部位。其发生于主支气管极为罕见。本病例报告了一名30岁女性,有劳力性呼吸困难和咯血症状,她患有一个体积大、位置深、边缘浸润且非典型核分裂象增多的血管球瘤。这些特征提示有恶性行为。然而,关于发生于支气管的血管球瘤的数据很少,必须强调在诊断此病例为恶性血管球瘤时需谨慎。因此,倾向于诊断为具有不确定恶性潜能的支气管血管球瘤。据我们所知,这种血管球瘤的类型和位置都极为罕见。由于关于发生于支气管的血管球瘤的数据很少,需要积累更多病例以明确其诊断和意义。