Acharya Sudeep, Anwar Shamsuddin, Thapa Kumar, Thapa Sakura, Lau Michael
Pulmonary and Critical Care Medicine, Staten Island University Hospital, Staten Island, USA.
Infectious Diseases, Tufts Medical Center, Boston, USA.
Cureus. 2023 May 7;15(5):e38684. doi: 10.7759/cureus.38684. eCollection 2023 May.
Glomus tumors, which account for less than 2% of soft tissue tumors, are a rare benign soft tissue neoplasm. They originated from neuro-myo-arterial glomus tissue whose primary function is regulation of the body temperature. This tissue is commonly located in the dermis or subcutis in the subungual region; however, it can be extracutaneous such as in bones, the genitourinary tract, the gastrointestinal tract, and the respiratory tract. Histologically, a glomus tumor is made of proliferating rounded or cuboidal epithelioid cells in a meshwork of blood vessels. Although a benign growth, they can rarely show malignant features with infiltration of surrounding tissue with the rapid multiplication of cells in which case it is labeled as a malignant glomus tumor. Pulmonary glomus tumors are extremely rare and most commonly occur in middle-aged men. They are mostly asymptomatic, but a small percentage of patients may present with hemoptysis and cough if there is large airway involvement. We present an interesting case of a middle-aged man presenting with cough and occasional hemoptysis, found to have an endobronchial nodular lesion, and subsequently diagnosed with a pulmonary glomus tumor.
血管球瘤占软组织肿瘤的比例不到2%,是一种罕见的良性软组织肿瘤。它们起源于神经 - 肌 - 动脉血管球组织,其主要功能是调节体温。这种组织通常位于甲下区域的真皮或皮下组织中;然而,它也可以位于皮肤外,如骨骼、泌尿生殖道、胃肠道和呼吸道。从组织学上看,血管球瘤由在血管网中增殖的圆形或立方形上皮样细胞组成。虽然是良性生长,但它们很少会表现出恶性特征,即细胞快速增殖并浸润周围组织,在这种情况下会被标记为恶性血管球瘤。肺血管球瘤极其罕见,最常见于中年男性。它们大多无症状,但如果累及大气道,一小部分患者可能会出现咯血和咳嗽。我们报告了一例有趣的病例,一名中年男性出现咳嗽和偶尔咯血,发现有支气管内结节性病变,随后被诊断为肺血管球瘤。