Van Der Sluis J J, Menke H E
Br J Vener Dis. 1975 Jun;51(3):158-60. doi: 10.1136/sti.51.3.158.
It is demonstrated that IgG fractions with isoelectric points above 7.6, isolated from pooled syphilitic sera, are able to elevate the thymol turbidity. The effect increases with increasing isoelectric points of the isolated fraction. IgG from individual syphilitic patients exerts a stronger effect on the thymol turbidity than normal IgG. It is concluded that elevated amounts of these basic immunoglobulins are present in the sera of syphilitic subjects.
已证实,从合并的梅毒血清中分离出的等电点高于7.6的IgG组分能够提高麝香草酚浊度。随着分离组分等电点的增加,这种效应增强。来自个别梅毒患者的IgG对麝香草酚浊度的影响比正常IgG更强。得出的结论是,梅毒患者血清中存在这些碱性免疫球蛋白的量增加。