Van Der Sluis J J, Menke H E, Neumann H
Br J Vener Dis. 1975 Jun;51(3):161-4. doi: 10.1136/sti.51.3.161.
By differential IgG measurements of sera of 27 patients with early infectious syphilis, it was found that infection with T. pallidium results in a preferential synthesis of IgG immunoglobulins characterized by high isoelectric points. The decrease in total IgG level observed after 6 weeks of treatment can to a large extent be accounted for by the decrease in basic IgG concentration. The relationship between the total and basic IgG levels and the number of T. pallidum present in the body during the three early stages of the disease studied is discussed.
通过对27例早期感染性梅毒患者血清进行IgG差异测量,发现感染梅毒螺旋体导致优先合成具有高电泳等位点特征的IgG免疫球蛋白。治疗6周后观察到的总IgG水平下降在很大程度上可归因于碱性IgG浓度的降低。本文讨论了在研究的疾病三个早期阶段中,总IgG和碱性IgG水平与体内梅毒螺旋体数量之间的关系。