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Plasma interferon-gamma-inducible protein 10 can be used to predict viral load in HIV-1-infected individuals.血浆干扰素-γ诱导蛋白10可用于预测HIV-1感染个体的病毒载量。
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Elevated plasma levels of IP-10 and MIG are early predictors of loss of control among elite HIV controllers.IP-10 和 MIG 血浆水平升高是精英 HIV 控制者失控的早期预测指标。
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The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression.在原发性 HIV 感染期间,CXCL9、CXCL10 和 CXCL11 水平的联合预测了 HIV 疾病的进展。
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Plasma interferon-gamma-inducible protein-10 can predict virologic response to hepatitis C virus therapy in HIV/HCV-coinfected patients with HCV genotype 1.血浆干扰素-γ诱导蛋白10可预测HIV/HCV合并感染且丙肝病毒基因型为1型患者对丙肝病毒治疗的病毒学反应。
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Brief Report: Interferon-γ-Inducible Protein 10-A Potential Marker for Targeted Viral Load Monitoring of Antiretroviral Treatment?简报:γ-干扰素诱导蛋白 10——一种用于抗逆转录病毒治疗靶向病毒载量监测的潜在标志物?
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IP-10 Promotes Latent HIV Infection in Resting Memory CD4 T Cells LIMK-Cofilin Pathway.IP-10 通过 LIMK-Cofilin 通路促进静息记忆性 CD4 T 细胞中的潜伏 HIV 感染。
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Biomarkers of Progression after HIV Acute/Early Infection: Nothing Compares to CD4⁺ T-cell Count?HIV 急性/早期感染后进展的生物标志物:没有什么比 CD4⁺ T 细胞计数更重要?
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Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo.体内α干扰素亚型对HIV-1感染的特异性抑制作用
J Virol. 2016 Jun 10;90(13):6001-6013. doi: 10.1128/JVI.00451-16. Print 2016 Jul 1.
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High IP-10 levels decrease T cell function in HIV-1-infected individuals on ART.在接受抗逆转录病毒治疗的HIV-1感染者中,高IP-10水平会降低T细胞功能。
J Leukoc Biol. 2014 Dec;96(6):1055-63. doi: 10.1189/jlb.3A0414-232RR. Epub 2014 Aug 25.

本文引用的文献

1
Plasma interferon-gamma-inducible protein-10 (IP-10) levels during acute hepatitis C virus infection.急性丙型肝炎病毒感染期间的血浆干扰素-γ诱导蛋白-10(IP-10)水平。
Hepatology. 2013 Jun;57(6):2124-34. doi: 10.1002/hep.26263. Epub 2013 May 8.
2
Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection.急性血浆生物标志物可预测 HIV-1 感染中的 T 细胞激活基准水平和疾病进展。
PLoS One. 2012;7(10):e46143. doi: 10.1371/journal.pone.0046143. Epub 2012 Oct 2.
3
Genital Inflammation Predicts HIV-1 Shedding Independent of Plasma Viral Load and Systemic Inflammation.生殖器炎症可预测 HIV-1 脱落,与血浆病毒载量和全身炎症无关。
J Acquir Immune Defic Syndr. 2012 Dec 1;61(4):436-40. doi: 10.1097/QAI.0b013e31826c2edd.
4
Plasma IP-10 is associated with rapid disease progression in early HIV-1 infection.血浆 IP-10 与早期 HIV-1 感染中的快速疾病进展相关。
Viral Immunol. 2012 Aug;25(4):333-7. doi: 10.1089/vim.2012.0011. Epub 2012 Jul 12.
5
Effect of standard tuberculosis treatment on plasma cytokine levels in patients with active pulmonary tuberculosis.标准抗结核治疗对活动性肺结核患者血浆细胞因子水平的影响。
PLoS One. 2012;7(5):e36886. doi: 10.1371/journal.pone.0036886. Epub 2012 May 14.
6
The suppression of immune activation during enfuvirtide-based salvage therapy is associated with reduced CCR5 expression and decreased concentrations of circulating interleukin-12 and IP-10 during 48 weeks of longitudinal follow-up.在依非韦伦为基础的挽救治疗期间,免疫激活的抑制与 CCR5 表达的减少以及在 48 周的纵向随访期间循环白细胞介素-12 和 IP-10 浓度的降低有关。
HIV Med. 2011 Feb;12(2):65-77. doi: 10.1111/j.1468-1293.2010.00848.x.
7
Interferon gamma-inducible protein 10: a predictive marker of successful treatment response in hepatitis C virus/HIV-coinfected patients.干扰素γ诱导蛋白10:丙型肝炎病毒/艾滋病病毒合并感染患者治疗成功应答的预测标志物
J Acquir Immune Defic Syndr. 2007 Jul 1;45(3):262-8. doi: 10.1097/QAI.0b013e3180559219.
8
Cerebrospinal fluid interferon-gamma-inducible protein 10 (IP-10, CXCL10) in HIV-1 infection.HIV-1感染中的脑脊液干扰素-γ诱导蛋白10(IP-10,CXCL10)
J Neuroimmunol. 2005 Nov;168(1-2):154-63. doi: 10.1016/j.jneuroim.2005.07.002. Epub 2005 Aug 8.
9
The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin.γ干扰素诱导蛋白(IP - 10)在人类皮肤迟发型免疫反应中的表达
J Exp Med. 1987 Oct 1;166(4):1098-108. doi: 10.1084/jem.166.4.1098.

Plasma interferon-gamma-inducible protein 10 can be used to predict viral load in HIV-1-infected individuals.

作者信息

Gray Clive M, Hong Heather A, Young Katherine, Lewis David A, Fallows Dorothy, Manca Claudia, Kaplan Gilla

出版信息

J Acquir Immune Defic Syndr. 2013 Jul 1;63(3):e115-6. doi: 10.1097/QAI.0b013e3182930ea8.

DOI:10.1097/QAI.0b013e3182930ea8
PMID:23760095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3682795/
Abstract
摘要