Department of Dermatology, Malabar Institute of Medical Sciences Hospital, Govindapuram P.O. Calicut, Kerala, India.
Indian J Dermatol Venereol Leprol. 2013 Jul-Aug;79(4):545-50. doi: 10.4103/0378-6323.113104.
Despite considerable overlap, the confusion hovering over the four common sparing signs can be cleared as follows: Reverse Koebner relates to sparing by physical trauma; isotopic non-response/reverse isotopic response relates to sparing over an already healed dermatosis; Renbok Phenomenon relates to sparing among two concomitant active diseases often with autoimmune etiology; anatopic phenomenon relates to sparing caused by presence of certain infectious diseases of skin. In conclusion, sparing phenomenon of dermatology seems to command our attention by their sheer number, variety, and clinical implications. Therefore, it may be said that astute clinician is the one who will look, not only for the presence of lesions in the patient but also for the conspicuous absence thereof.
尽管存在相当大的重叠，但以下可以澄清四种常见的皮损消退迹象的混淆：反向 Koebner 与物理创伤引起的皮损消退有关；同位素无反应/反向同位素反应与已治愈的皮肤病皮损消退有关；Renbok 现象与两种同时存在的自身免疫性病因的活跃疾病有关；解剖位置现象与某些皮肤传染病引起的皮损消退有关。总之，皮肤病的皮损消退现象因其数量、种类和临床意义而引起我们的关注。因此，可以说，敏锐的临床医生不仅会观察患者是否存在皮损，还会注意到明显的缺失。
