North-East Thames London Deanery, Broomfield Hospital, Chelmsford, Essex, UK.
Clin Med (Lond). 2013 Jun;13(3):312-4. doi: 10.7861/clinmedicine.13-3-312.
Takotsubu cardiomyopathy (TC) describes transient left ventricular apical ballooning due to akinetic myocardium. It mimics acute coronary syndrome, with similar electrocardiogram changes and raised troponin, but visible coronary artery stenosis is missing. Patients usually recall a preceding stressful event and post-menopausal women are at greatest risk. Aetiology of TC remains contentious, but the strongest theory suggests increased sympathetic nervous system activity resulting in elevated catecholamines, which culminates in cardiac manifestations. Treatment is supportive and complications include arrhythmias, cardiac rupture, thrombus formation and congestive cardiac failure. The prognosis is favourable and by definition cardiac function returns to pre-morbid levels. Mortality is rare (1–2%).
心尖球囊样综合征（TC）描述了由于心肌运动障碍导致的短暂性左心室心尖气球样变。它类似于急性冠状动脉综合征，具有相似的心电图改变和升高的肌钙蛋白，但没有可见的冠状动脉狭窄。患者通常会回忆起之前的压力事件，而绝经后妇女的风险最大。TC 的病因仍有争议，但最强的理论表明，交感神经系统活动增加导致儿茶酚胺升高，最终导致心脏表现。治疗是支持性的，并发症包括心律失常、心脏破裂、血栓形成和充血性心力衰竭。预后良好，根据定义，心脏功能恢复到发病前水平。死亡率很低（1-2%）。
