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青少年神经性厌食症住院患者的躯体结局:报告的障碍及与总体结局的关联。

Somatic outcome among patients hospitalised for anorexia nervosa in adolescence: disorders reported and links with global outcome.

机构信息

Department of Psychiatry, Institut Mutualiste Montsouris, Paris, France.

出版信息

Eat Weight Disord. 2013 Jun;18(2):175-82. doi: 10.1007/s40519-013-0030-2. Epub 2013 May 9.

Abstract

AIMS

(1) To describe the frequency of somatic pathologies and depression among former anorexia nervosa (AN) patients; (2) to study links with subjects' clinical history and global outcomes.

METHODS

97 women hospitalised for AN during adolescence, 9.00 ± 1.92 years previously, were interviewed using structured questionnaires concerning somatic and psychiatric disorders that they had experienced.

RESULTS

Iron deficiency, migraine, cystitis, upper digestive system disorders, fractures, osteoporosis, and dental problems were reported with a frequency >20 %. Depression was reported by 2/3 of the sample. Osteoporosis was 14 times more frequent in case of vitamin D deficiency. Fractures were three times more frequent in presence of osteoporosis and less frequent when the overall outcome was better.

CONCLUSION

Among women who had AN in adolescence, somatic comorbidities are frequent in adulthood. They are linked to the severity and the duration of AN, and to the overall outcome of the subject.

摘要

目的

(1)描述青春期前厌食症(AN)患者躯体疾病和抑郁的发生频率;(2)研究与患者临床病史和总体结局的关系。

方法

97 名曾在青春期因 AN 住院的女性患者,9.00±1.92 年前入院,使用结构化问卷对她们经历过的躯体和精神障碍进行了访谈。

结果

报告的铁缺乏、偏头痛、膀胱炎、上消化道系统疾病、骨折、骨质疏松症和牙齿问题的发生率>20%。2/3的样本报告了抑郁。维生素 D 缺乏症使骨质疏松症的发生频率增加 14 倍。骨质疏松症患者骨折的发生率增加了两倍,而总体结局较好时骨折的发生率则降低。

结论

在青春期患有 AN 的女性中,成年后躯体合并症较为常见。它们与 AN 的严重程度和持续时间以及受试者的总体结局有关。

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