Vivarium, Tartu University, 50090 Tartu, Estonia.
Lab Anim. 2013 Jul;47(3):220-2. doi: 10.1177/0023677213489280. Epub 2013 May 16.
The effect of environmental enrichment in the form of a cage shelf on the behaviour of male C57BL/6 and BALB/c mice was compared. Male C57BL/6 and BALB/c mice were randomly allocated into 12 cages per strain. The mice were kept in control conditions or exposed to a cage shelf for two, four, six or eight weeks, and thereafter assessed with the elevated plus maze. C57BL/6 mice displayed a trend of being less anxious than the BALB/c mice. A cage shelf increased the number of entries made into the open arms and the total number of entries only in the case of the C57BL/6 mice, but had no effect on the behaviour of the BALB/c mice. In conclusion, the effect of a cage shelf on the elevated plus maze behaviour of mice depends on the strain of the animals.
以笼架形式进行环境丰容对雄性 C57BL/6 和 BALB/c 小鼠行为的影响进行了比较。雄性 C57BL/6 和 BALB/c 小鼠被随机分配到每品系 12 个笼子中。将小鼠置于对照条件下或暴露于笼架中 2、4、6 或 8 周，然后用高架十字迷宫进行评估。C57BL/6 小鼠表现出比 BALB/c 小鼠焦虑程度低的趋势。笼架仅在 C57BL/6 小鼠的情况下增加了进入开放臂的次数和总进入次数，但对 BALB/c 小鼠的行为没有影响。总之，笼架对小鼠高架十字迷宫行为的影响取决于动物的品系。
