Jindal Rashmi, Jain Anshu, Gupta Alpa, Shirazi Nadia
Department of Dermatology, Himalayan Institute Hospital Trust, Dehradun, Uttaranchal, India.
BMJ Case Rep. 2013 Jun 10;2013:bcr2012007008. doi: 10.1136/bcr-2012-007008.
Ash-leaf spots, a diagnostic manifestation of tuberous sclerosis complex, are sometimes difficult to differentiate from other hypopigmented lesions. Vitiligo, naevus anaemicus and naevus depigmentosus are important clinical differentials for ash-leaf spots. Among these naevus depigmentosus poses maximum difficulty because of clinical as well as histological similarities. Here we describe a 6-month-old child with multiple segmental hypopigmented macules over the face. In isolation lesions appeared to be those of naevus depigmentosus. However, the presence of other manifestations of tuberous sclerosis favoured the diagnosis of ash-leaf spots. Important similarities and differences between the two have also been discussed.
色素脱失斑是结节性硬化症的一种诊断性表现，有时难以与其他色素减退性皮损相鉴别。白癜风、贫血痣和色素脱失痣是色素脱失斑重要的临床鉴别诊断。其中，色素脱失痣由于临床及组织学上的相似性而造成最大鉴别困难。在此，我们描述一名6个月大儿童，面部有多处节段性色素减退斑。孤立的皮损看似色素脱失痣。然而，结节性硬化症的其他表现支持色素脱失斑的诊断。本文还讨论了两者重要的异同点。
