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用于组织消融的同时空间和时间聚焦

Simultaneous spatial and temporal focusing for tissue ablation.

作者信息

Block Erica, Greco Michael, Vitek Dawn, Masihzadeh Omid, Ammar David A, Kahook Malik Y, Mandava Naresh, Durfee Charles, Squier Jeff

机构信息

Department of Physics, Colorado School of Mines, 1523 Illinois Street, Golden, CO 80401, USA.

出版信息

Biomed Opt Express. 2013 May 8;4(6):831-41. doi: 10.1364/BOE.4.000831. Print 2013 Jun 1.

DOI:10.1364/BOE.4.000831
PMID:23761847
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3675863/
Abstract

Simultaneous spatial temporal focusing (SSTF) is used to deliver microjoule femtosecond pulses with low numerical aperture geometries (<0.05 NA) with characteristics that are significantly improved compared to standard focusing paradigms. Nonlinear effects that would normally result in focal plane shifts and focal spot distortion are mitigated when SSTF is employed. As a result, it is shown that SSTF will enable surgical implementations that are presently inhibited.

摘要

同时空聚焦（SSTF）用于以低数值孔径几何结构（<0.05 NA）传输微焦耳级飞秒脉冲，其特性与标准聚焦模式相比有显著改善。当采用SSTF时，通常会导致焦平面偏移和焦点光斑畸变的非线性效应会得到缓解。结果表明，SSTF将使目前受到限制的手术应用成为可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/4510dbfbd9d5/boe-4-6-831-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/17f70b94aaae/boe-4-6-831-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/bc74124c5781/boe-4-6-831-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/fb25a5256681/boe-4-6-831-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/86f8b848ff28/boe-4-6-831-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/dfdaead0c3cc/boe-4-6-831-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/04c637944e2c/boe-4-6-831-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/5f8abcc3f4d6/boe-4-6-831-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/cbb263cd0896/boe-4-6-831-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/f33bc47d107a/boe-4-6-831-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/73a3a63e636b/boe-4-6-831-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/4510dbfbd9d5/boe-4-6-831-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/17f70b94aaae/boe-4-6-831-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/bc74124c5781/boe-4-6-831-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/fb25a5256681/boe-4-6-831-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/86f8b848ff28/boe-4-6-831-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/dfdaead0c3cc/boe-4-6-831-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/04c637944e2c/boe-4-6-831-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/5f8abcc3f4d6/boe-4-6-831-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/cbb263cd0896/boe-4-6-831-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/f33bc47d107a/boe-4-6-831-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/73a3a63e636b/boe-4-6-831-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8855/3675863/4510dbfbd9d5/boe-4-6-831-g011.jpg

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