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Simulation of electrophoretic stretching of DNA in a microcontraction using an obstacle array for conformational preconditioning.使用障碍物阵列进行构象预处理模拟微收缩过程中 DNA 的电泳拉伸。
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Entropic trap, surface-mediated combing, and assembly of DNA molecules within submicrometer interfacial confinement.熵陷阱、表面介导梳理以及亚微米界面限制内DNA分子的组装
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Dynamics of individual flexible polymers in a shear flow.剪切流中单个柔性聚合物的动力学
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聚合物在两相微流中的拉伸:壁面润湿性的影响。

Polymer stretch in two-phase microfluidics: Effect of wall wettability.

机构信息

Department of Chemical Engineering, National Taiwan University, Taipei 106, Taiwan.

出版信息

Biomicrofluidics. 2012 Jun 13;6(2):24130. doi: 10.1063/1.4729129. Print 2012 Jun.

DOI:10.1063/1.4729129
PMID:23762212
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3386991/
Abstract

Polymer stretching in two-phase microfluidics is investigated by dissipative particle dynamics. The flow patterns can be controlled by wall wettability, flowrate ratio between two phases, and Reynolds number (Re). For neutral and partially wettable walls, segmented flows are formed and polymer stretching can be controlled by Re and segment length. At high Re, stratified flows are observed and the extension ratio can be tuned by the flowrate ratio. For nonwettable walls, slug flows are formed and polymer stretching can be controlled by Re and slug length. At high Re or flowrate ratio, annular flows are observed and high extension ratio can be easily attained.

摘要

通过耗散粒子动力学研究了两相间微流中的聚合物拉伸。通过壁面润湿性、两相流速比和雷诺数(Re)可以控制流型。对于中性和部分润湿的壁面,形成分段流,聚合物拉伸可以通过 Re 和段长来控制。在高 Re 下,观察到分层流,通过流速比可以调整延伸比。对于不润湿的壁面,形成弹状流,聚合物拉伸可以通过 Re 和弹状长度来控制。在高 Re 或流速比下,观察到环形流,很容易达到高延伸比。