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在一个避孕药具获取受限和终止妊娠受限的国家进行紧急避孕:一项前瞻性随访研究。

Emergency contraception in a country with restricted access to contraceptives and termination of pregnancy, a prospective follow-up study.

机构信息

Fertility and Sterility Research Centre, Warsaw, Poland.

出版信息

Acta Obstet Gynecol Scand. 2013 Oct;92(10):1183-7. doi: 10.1111/aogs.12198. Epub 2013 Jul 18.

Abstract

OBJECTIVE

Poland has a restrictive abortion law. Emergency contraception (EC) is expensive and available only on prescription, which is not easily obtainable in public health care. We aimed to identify the main reasons for EC requests, observed failure rates and the type and incidence of adverse effects.

DESIGN

Prospective single-center observational study.

POPULATION

A cohort of women living in Warsaw, who requested EC.

METHODS

Data were collected via a questionnaire completed by healthcare providers prescribing EC, and included age, date of the request, previous EC use, time from intercourse to clinic visit and day of menstrual cycle on which intercourse took place.

MAIN OUTCOME MEASURES

Reason for EC request, time lapse between unprotected intercourse and EC use, age of women requesting EC, reported cases of pregnancy.

RESULTS

A total of 4655 women requested EC. Of these 62.9% (n = 2928) were ≤25 years old. During follow up, 0.75% (31 individuals) became pregnant. Adverse effects of hormonal EC were rare and mild. The main reason for requesting EC was problems associated with condoms (63.2%, n = 2609). The mean interval between unprotected intercourse and EC use was 21.2 h, but 26.7 h when EC failed (n.s.). Considering intake within and after 24 h, the difference was significant (p < 0.05).

CONCLUSIONS

Women living in Warsaw seeking EC used the EC product very soon after unprotected intercourse, and this was probably one of the most important reasons for the low pregnancy rates in the studied population.

摘要

目的

波兰施行限制堕胎法。紧急避孕(EC)费用昂贵,且只能凭处方购买,在公共医疗保健中不易获得。我们旨在确定 EC 请求的主要原因、观察到的失败率以及不良反应的类型和发生率。

设计

前瞻性单中心观察性研究。

人群

居住在华沙的要求 EC 的女性队列。

方法

通过医疗保健提供者填写的问卷收集数据,包括年龄、请求日期、以前是否使用过 EC、从性行为到诊所就诊的时间以及发生性行为的月经周期天数。

主要观察指标

EC 请求的原因、无保护性行为和 EC 使用之间的时间间隔、要求 EC 的女性年龄、报告的怀孕病例。

结果

共有 4655 名女性要求 EC。其中 62.9%(n=2928)年龄≤25 岁。在随访期间,0.75%(31 人)怀孕。激素 EC 的不良反应罕见且轻微。要求 EC 的主要原因是与避孕套相关的问题(63.2%,n=2609)。无保护性行为和 EC 使用之间的平均间隔时间为 21.2 小时,但 EC 失败时为 26.7 小时(无统计学意义)。考虑到 24 小时内和之后的摄入,差异有统计学意义(p<0.05)。

结论

居住在华沙的寻求 EC 的女性在无保护性行为后很快使用 EC 产品,这可能是研究人群中低妊娠率的最重要原因之一。

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