Wahab Shahid, Faiz-ur-Rab Khowaja, Das Hargun Lakhani
Ophthalmology Unit II, Dow University of Health Sciences, Civil Hospital, Karachi.
J Coll Physicians Surg Pak. 2013 Jun;23(6):401-4.
To get optimal visualization of fundus by early phacoemulsification in diabetic cataract for early recognition and management of diabetic macular oedema.
Interventional study.
Ophthalmology Unit III, Sindh Government Lyari General Hospital and Dow University of Health Sciences and Al-Noor Eye Hospital, Karachi, from July 2008 to June 2009.
Patients with uncontrolled type-II diabetes mellitus of more than 10 years of duration were selected. Patients with clinical significant macular oedema (CSME), non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) were excluded. Follow-up was done on day 1, 1 week, 1 month, 3 months and 6 months.
The male to female ratio was 1:1.44. Out of 218 patients; 129 (59.2%) were males and 89 (40.8%) were females. CSME was found in 82 patients (37.6%) at first postoperative week which declined to 29 cases (13.3%) at first month follow-up. Three subjects developed mild to moderate NPDR. In majority of the subjects, best corrected visual acuity (BCVA) gradually improved in each subsequent follow-up visit.
Early phacoemulsification in diabetic cataract offers optimal posterior pole visualization and clears the ambiguity of decreased vision either caused by cataract or macular oedema. Uncomplicated phacoemulsification does not accelerate diabetic macular oedema or retinopathy provided glycemic control and co-morbids are well addressed.
通过对糖尿病性白内障进行早期超声乳化术,以实现眼底的最佳可视化,从而早期识别和处理糖尿病性黄斑水肿。
干预性研究。
2008年7月至2009年6月,在信德省政府利亚里综合医院眼科三室、道健康科学大学以及卡拉奇的阿尔努尔眼科医院。
选取病程超过10年且血糖控制不佳的II型糖尿病患者。排除患有临床显著性黄斑水肿(CSME)、非增殖性糖尿病视网膜病变(NPDR)和增殖性糖尿病视网膜病变(PDR)的患者。在术后第1天、1周、1个月、3个月和6个月进行随访。
男女比例为1:1.44。218例患者中,129例(59.2%)为男性,89例(40.8%)为女性。术后第1周,82例患者(37.6%)出现CSME,在第1个月随访时降至29例(13.3%)。3名受试者发展为轻度至中度NPDR。在大多数受试者中,每次后续随访时最佳矫正视力(BCVA)逐渐改善。
糖尿病性白内障早期超声乳化术可实现最佳的后极部可视化,消除由白内障或黄斑水肿导致的视力下降的不确定性。只要血糖控制和合并症得到妥善处理,单纯的超声乳化术不会加速糖尿病性黄斑水肿或视网膜病变。