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类风湿关节炎与骨关节炎患者接受全膝关节置换术:围手术期结果。

Rheumatoid arthritis vs osteoarthritis in patients receiving total knee arthroplasty: perioperative outcomes.

机构信息

Department of Anesthesiology, Hospital for Special Surgery, Weill Medical, College of Cornell University, New York, New York; Department of Anesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University, Salzburg, Salzburg, Austria.

Department of Public Health, Division of Biostatistics and Epidemiology, Weill Medical College of Cornell University, New York, New York.

出版信息

J Arthroplasty. 2014 Feb;29(2):308-13. doi: 10.1016/j.arth.2013.05.008. Epub 2013 Jun 12.

Abstract

There is a paucity of data available on perioperative outcomes of patients undergoing total knee arthroplasty (TKA) for rheumatoid arthritis (RA). We determined differences in demographics and risk for perioperative adverse events between patients suffering from osteoarthritis (OA) versus RA using a population-based approach. Of 351,103 entries for patients who underwent TKA, 3.4% had a diagnosis of RA. RA patients were on average younger [RA: 64.3 years vs OA: 66.6 years; P<0.001] and more likely female [RA: 79.2% vs OA: 63.2%; P<0. 001]. The unadjusted rates of mortality and most major perioperative adverse events were similar in both groups, with the exception of infection [RA: 4.5% vs. OA: 3.8%; P<0.001]. RA was not associated with increased adjusted odds for combined adverse events.

摘要

类风湿关节炎(RA)患者行全膝关节置换术(TKA)的围手术期结局相关数据较为匮乏。我们采用基于人群的方法,确定了 OA 与 RA 患者在围手术期不良事件风险方面的人口统计学差异。在接受 TKA 的 351103 名患者中,有 3.4%的患者诊断为 RA。RA 患者的平均年龄更小[RA:64.3 岁 vs OA:66.6 岁;P<0.001],女性比例更高[RA:79.2% vs OA:63.2%;P<0.001]。两组患者的死亡率和大多数主要围手术期不良事件的未调整发生率相似,除感染外[RA:4.5% vs. OA:3.8%;P<0.001]。RA 与调整后不良事件的综合发生几率增加无关。

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