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1
Epilepsy, cognition, and neuropsychiatry (Epilepsy, Brain, and Mind, part 2).癫痫、认知和神经精神病学(癫痫、大脑和思维,第 2 部分)。
Epilepsy Behav. 2013 Aug;28(2):283-302. doi: 10.1016/j.yebeh.2013.03.012. Epub 2013 Jun 10.
2
[Psychological and social implications of epilepsy in adolescents].[青少年癫痫的心理和社会影响]
Rev Neurol. 1999;28(1):43-9.
3
The aspects and mechanisms of cognitive alterations in epilepsy: the role of antiepileptic medications.癫痫认知改变的方面和机制:抗癫痫药物的作用。
CNS Neurosci Ther. 2009 Summer;15(2):134-56. doi: 10.1111/j.1755-5949.2008.00062.x. Epub 2009 Feb 26.
4
[Cognition and epilepsies].[认知与癫痫]
Nervenarzt. 2008 Sep;79 Suppl 2:77-91; quiz 92. doi: 10.1007/s00115-008-2463-9.
5
Neurobiological evidence for epilepsy-induced interictal disturbances.癫痫诱发发作间期障碍的神经生物学证据。
Adv Neurol. 1991;55:97-111.
6
Cognitive disorders in epilepsy I: Clinical experience, real-world evidence and recommendations.癫痫相关认知障碍 I:临床经验、真实世界证据与推荐意见。
Seizure. 2020 Dec;83:216-222. doi: 10.1016/j.seizure.2020.10.009. Epub 2020 Oct 14.
7
Effect of seizures and epileptiform discharges on cognitive function.癫痫发作和癫痫样放电对认知功能的影响。
Epilepsia. 1997;38 Suppl 1:S52-5. doi: 10.1111/j.1528-1157.1997.tb04520.x.
8
Cognitive and Social Outcomes of Epileptic Encephalopathies.癫痫性脑病的认知和社会结局
Semin Pediatr Neurol. 2017 Nov;24(4):264-275. doi: 10.1016/j.spen.2017.10.001. Epub 2017 Oct 7.
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[Epilepsy and cognitive dysfunction].
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Correspondence on ''the unrecognized epilepsy spectrum: the effects of levetiracetam on neuropsychological functioning in relation to subclinical spike production''.关于“未被识别的癫痫谱系:左乙拉西坦对与亚临床棘波产生相关的神经心理功能的影响”的通信
J Child Neurol. 2009 Dec;24(12):1578; author reply 1579. doi: 10.1177/0883073809347800.

引用本文的文献

1
Associations between neurolinguistic deficits and personality traits in people with epilepsy.癫痫患者神经语言缺陷与人格特质之间的关联。
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2
Modulation of GABA receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks.岛叶中γ-氨基丁酸(GABA)受体的调节双向影响癫痫大鼠在空间和非空间操作性任务中的联合记忆。
Front Behav Neurosci. 2023 Jan 4;16:1042227. doi: 10.3389/fnbeh.2022.1042227. eCollection 2022.
3
Recurrent Hippocampo-neocortical sleep-state divergence in humans.人类海马体-新皮质睡眠状态的反复分离。
Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2123427119. doi: 10.1073/pnas.2123427119. Epub 2022 Oct 24.
4
Magnetoencephalography can reveal deep brain network activities linked to memory processes.脑磁图可以揭示与记忆过程相关的深部大脑网络活动。
Hum Brain Mapp. 2022 Oct 15;43(15):4733-4749. doi: 10.1002/hbm.25987. Epub 2022 Jun 29.
5
Temporal Lobe Epilepsy and Psychiatric Comorbidity.颞叶癫痫与精神共病
Front Neurol. 2021 Nov 30;12:775781. doi: 10.3389/fneur.2021.775781. eCollection 2021.
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The Blood-Brain Barrier: Much More Than a Selective Access to the Brain.血脑屏障:远不止是进入大脑的选择性通道。
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Disentangling neocortical alpha/beta and hippocampal theta/gamma oscillations in human episodic memory formation.解析人类情景记忆形成中的新皮层α/β和海马θ/γ振荡。
Neuroimage. 2021 Nov 15;242:118454. doi: 10.1016/j.neuroimage.2021.118454. Epub 2021 Aug 4.
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Bibliography: Clinical Neuropsychiatry.参考文献:《临床神经精神病学》
Focus (Am Psychiatr Publ). 2016 Oct;14(4):488-489. doi: 10.1176/appi.focus.140404. Epub 2016 Oct 7.
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Mood Disorders in Epilepsy.癫痫中的情绪障碍
Focus (Am Psychiatr Publ). 2016 Oct;14(4):465-472. doi: 10.1176/appi.focus.20160017. Epub 2016 Oct 7.
10
Tau deposition in young adults with drug-resistant focal epilepsy.tau 沉积与耐药性局灶性癫痫的年轻患者。
Epilepsia. 2019 Dec;60(12):2398-2403. doi: 10.1111/epi.16375. Epub 2019 Oct 29.

本文引用的文献

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Risks and benefits of (pharmaco)epidemiology.(药物)流行病学的风险与收益。
Ther Adv Drug Saf. 2011 Jun;2(3):95-102. doi: 10.1177/2042098611404920.
2
Catastrophising and normalising in patient's accounts of their seizure experiences.患者对自身癫痫发作经历的描述中存在灾难化和正常化现象。
Seizure. 2012 Dec;21(10):795-801. doi: 10.1016/j.seizure.2012.09.007. Epub 2012 Oct 4.
3
Epilepsy, suicidality, and psychiatric disorders: a bidirectional association.癫痫、自杀倾向和精神障碍:双向关联。
Ann Neurol. 2012 Aug;72(2):184-91. doi: 10.1002/ana.23601. Epub 2012 Aug 7.
4
5-HT(1A) receptor binding changes in patients with major depressive disorder before and after antidepressant treatment: a pilot [¹⁸F]MPPF positron emission tomography study.抗抑郁治疗前后重性抑郁障碍患者 5-HT(1A) 受体结合的变化:一项先导性 [¹⁸F]MPPF 正电子发射断层扫描研究。
Psychiatry Res. 2012 Jul 30;203(1):103-4. doi: 10.1016/j.pscychresns.2011.09.001. Epub 2012 Aug 3.
5
Psychiatric history does not predict seizure outcome following temporal lobectomy for mesial temporal sclerosis.精神病史并不能预测内侧颞叶硬化症患者行颞叶切除术的术后癫痫发作结果。
Epilepsia. 2012 Oct;53(10):1700-4. doi: 10.1111/j.1528-1167.2012.03569.x. Epub 2012 Jun 27.
6
Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date.针对谷氨酸能系统治疗重度抑郁症:基本原理和迄今为止的进展。
Drugs. 2012 Jul 9;72(10):1313-33. doi: 10.2165/11633130-000000000-00000.
7
Methodologies used to identify and characterize interactions among antiepileptic drugs.用于识别和描述抗癫痫药物相互作用的方法。
Expert Rev Clin Pharmacol. 2012 May;5(3):281-92. doi: 10.1586/ecp.12.10.
8
Patterns of treatment response in newly diagnosed epilepsy.新诊断癫痫的治疗反应模式。
Neurology. 2012 May 15;78(20):1548-54. doi: 10.1212/WNL.0b013e3182563b19. Epub 2012 May 9.
9
Role of gabapentin enacarbil XR in restless legs syndrome.加巴喷丁恩卡必利 XR 在不宁腿综合征中的作用。
Ther Clin Risk Manag. 2012;8:201-8. doi: 10.2147/TCRM.S24436. Epub 2012 May 1.
10
Recording and analysis techniques for high-frequency oscillations.高频震荡的记录和分析技术。
Prog Neurobiol. 2012 Sep;98(3):265-78. doi: 10.1016/j.pneurobio.2012.02.006. Epub 2012 Mar 7.

癫痫、认知和神经精神病学(癫痫、大脑和思维,第 2 部分)。

Epilepsy, cognition, and neuropsychiatry (Epilepsy, Brain, and Mind, part 2).

机构信息

Sackler School of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

出版信息

Epilepsy Behav. 2013 Aug;28(2):283-302. doi: 10.1016/j.yebeh.2013.03.012. Epub 2013 Jun 10.

DOI:10.1016/j.yebeh.2013.03.012
PMID:23764496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5016028/
Abstract

Epilepsy is, of course, not one disease but rather a huge number of disorders that can present with seizures. In common, they all reflect brain dysfunction. Moreover, they can affect the mind and, of course, behavior. While animals too may suffer from epilepsy, as far as we know, the electrical discharges are less likely to affect the mind and behavior, which is not surprising. While the epileptic seizures themselves are episodic, the mental and behavioral changes continue, in many cases, interictally. The episodic mental and behavioral manifestations are more dramatic, while the interictal ones are easier to study with anatomical and functional studies. The following extended summaries complement those presented in Part 1.

摘要

癫痫当然不是一种疾病,而是大量可能出现癫痫发作的疾病。它们都反映了大脑功能障碍。此外,它们还可能影响大脑,当然还有行为。虽然动物也可能患有癫痫,但据我们所知,电放电不太可能影响大脑和行为,这并不奇怪。虽然癫痫发作本身是发作性的,但精神和行为变化仍在继续,在许多情况下,是发作间期的。发作性精神和行为表现更为明显,而发作间期的则更容易通过解剖学和功能研究进行研究。以下扩展摘要补充了第 1 部分中提出的内容。