早产儿视网膜病变筛查的替代方法：双目间接检眼镜与广角数字视网膜成像。
Alternative methods for the screening of retinopathy of prematurity: binocular indirect ophthalmoscopy vs wide-field digital retinal imaging.
机构信息
ROP Screening, Treatment and Training Center, Department of Ophthalmology, Etlik Zubeyde Hanim Maternity and Women's Health Research Hospital, Ankara, Turkey.
出版信息
Eye (Lond). 2013 Sep;27(9):1053-7. doi: 10.1038/eye.2013.128. Epub 2013 Jun 14.
Abstract
PURPOSE
To compare the diagnostic efficacy of wide-field digital retinal imaging (WFDRI) with binocular indirect ophthalmoscopy (BIO) for retinopathy of prematurity (ROP) screening.
METHODS
Premature infants admitted for ROP screening were included in this prospective, randomized and double-blind comparative study. They were examined by using BIO and WFDRI.
RESULTS
A total of 58 infants were enrolled in the study. The sensitivities of WFDRI in detecting any stage of ROP, treatment-requiring ROP and plus disease were 58.6, 100, and 100% respectively, with a specificity of 100% for all. The proportional agreement between WFDRI and BIO was 0.903 for detection of any stage of ROP, 1.0 for treatment-requiring ROP, and 1.0 for plus disease.
CONCLUSION
The sensitivity and specificity of WFDRI was excellent for the diagnosis of severe and treatment-requiring ROP. However, BIO was superior in mild ROP particularly for the ones in retinal periphery.
摘要
目的
比较广角数字视网膜成像（WFDRI）与双目间接检眼镜（BIO）在早产儿视网膜病变（ROP）筛查中的诊断效能。
方法
本前瞻性、随机、双盲对比研究纳入了接受 ROP 筛查的早产儿。他们接受了 BIO 和 WFDRI 检查。
结果
共有 58 例婴儿入组本研究。WFDRI 检测任何阶段 ROP、需治疗 ROP 和 plus 病的敏感度分别为 58.6%、100%和 100%，特异性均为 100%。WFDRI 与 BIO 检测任何阶段 ROP 的比例一致性为 0.903，检测需治疗 ROP 和 plus 病的比例一致性为 1.0。
结论
WFDRI 对严重和需治疗 ROP 的诊断具有极好的敏感性和特异性。然而，BIO 在轻度 ROP 特别是视网膜周边病变的诊断方面更具优势。
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