中国中老年人群中 OAB 的患病率及相关风险因素。

The prevalence and risk factors of OAB in middle-aged and old people in China.

机构信息

Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Institute of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Neurourol Urodyn. 2014 Apr;33(4):387-91. doi: 10.1002/nau.22429. Epub 2013 Jun 13.

DOI:10.1002/nau.22429

PMID:23765684

Abstract

AIMS

To evaluate the prevalence of associated risk factors of over active bladder (OAB) in people ≥40 years old in mainland of China.

METHODS

A randomized community-based, cross-sectional study was performed on 10,160 residents (≥40 years old) in the mainland of China using a questionnaire. The overactive bladder symptom score (OABSS) was filled upon site. The chi-square test was used to determine the differences of prevalence between sex, age groups, body mass index (BMI) and people with and without diabetes mellitus (DM).

RESULTS

A total of 9,805 (96.5%) subjects qualified for the final statistical analysis. The overall prevalence of OAB was 2.1% (209/9,805), of whom 1.0% had OABdry and 1.1% had OABwet . The prevalence of OAB was more common in men than in women over the age of 60 (4.6% vs. 2.6%, P < 0.05). The prevalence of OAB in subjects with DM was significantly higher than those without DM in patients with BMI ≥ 25 (P < 0.05). The subjects with a BMI over 29 were more likely to have OAB (3.2% vs. 1.8%, P < 0.05).

CONCLUSIONS

In this population, the prevalence of OAB increased with age for both sexes, but was higher for males over 60 years of age. The study also showed that diabetics with BMI ≥ 25 and people suffering from obesity are more likely to have OAB.

摘要

目的

评估中国大陆≥40 岁人群中膀胱过度活动症（OAB）相关危险因素的流行情况。

方法

采用随机、基于社区的横断面研究，对中国大陆 10160 名（≥40 岁）居民进行问卷调查。现场填写膀胱过度活动症状评分（OABSS）。采用卡方检验比较不同性别、年龄组、体质指数（BMI）和有/无糖尿病（DM）患者的患病率差异。

结果

共有 9805 名（96.5%）受试者符合最终统计分析的条件。OAB 的总体患病率为 2.1%（209/9805），其中 1.0%为 OABdry，1.1%为 OABwet。60 岁以上男性 OAB 的患病率高于女性（4.6%比 2.6%，P<0.05）。BMI≥25 的 DM 患者 OAB 的患病率明显高于无 DM 患者（P<0.05）。BMI 超过 29 的患者更可能患有 OAB（3.2%比 1.8%，P<0.05）。