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福州中国女性膀胱过度活动症综合征的患病率及危险因素

Prevalence and risk factors of overactive bladder syndrome in Fuzhou Chinese women.

作者信息

Zhang Wenju, Song Yanfeng, He Xiaoyu, Huang Huijuan, Xu Bo, Song Jian

机构信息

Department of Obstetrics and Gynecology, Dongfang Hospital, Fuzhou, China.

出版信息

Neurourol Urodyn. 2006;25(7):717-21. doi: 10.1002/nau.20293.

DOI:10.1002/nau.20293
PMID:16944449
Abstract

AIMS

We randomly sampled a community-based, healthy population to evaluate the prevalence and associated risk factors of overactive bladder (OAB) syndrome by using the International Continence Society (ICS) definition.

METHODS

We randomly sampled 6,066 women (3.0% of registered female residents aged 20 years and older in Fuzhou) and mailed Bristol Female Lower Urinary Tract Symptoms questionnaire for women self-completion. Women (4,684; 77.2%) with evaluable data were included in this study.

RESULTS

The prevalence of OAB was 8.0% (n = 377), OAB(dry) 2.4% (n = 114), and OAB(wet) 5.6% (n = 263), hence 30% had OAB(dry) and 70% OAB(wet.) The prevalence of OAB and OAB(wet) demonstrated an significant increasing with advancing age (P < 0.01). A multiple logistic regression analysis showed menopause, parity >2, constipation, episiotomy, and higher BMI were potential risk factors for OAB, constipation increased the occurrence of OAB(dry). OAB(wet) was associated with menopause, parity >2, higher fetal birthweight, episiotomy, while cesarean delivery protected against the development of OAB(wet).

CONCLUSIONS

The prevalence of OAB in chinese women is lower than that of most reports in Occidental women, and increases with advancing age. Many potential risk factors increase the occurrence of OAB.

摘要

目的

我们对一个基于社区的健康人群进行随机抽样,以使用国际尿控协会(ICS)的定义评估膀胱过度活动症(OAB)综合征的患病率及相关危险因素。

方法

我们随机抽取了6066名女性(占福州市20岁及以上注册女性居民的3.0%),并邮寄布里斯托尔女性下尿路症状问卷供女性自行填写。本研究纳入了有可评估数据的4684名女性(77.2%)。

结果

OAB的患病率为8.0%(n = 377),干性OAB为2.4%(n = 114),湿性OAB为5.6%(n = 263),因此30%为干性OAB,70%为湿性OAB。OAB和湿性OAB的患病率随年龄增长呈显著上升趋势(P < 0.01)。多因素logistic回归分析显示,绝经、产次>2、便秘、会阴切开术和较高的体重指数是OAB的潜在危险因素,便秘增加了干性OAB的发生风险。湿性OAB与绝经、产次>2、较高的出生体重、会阴切开术有关,而剖宫产可预防湿性OAB的发生。

结论

中国女性OAB的患病率低于大多数西方女性的报道,且随年龄增长而增加。许多潜在危险因素会增加OAB的发生风险。

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