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难治性精神分裂症非紧张性缄默症对维持性电休克治疗和抗精神病药物联合治疗有反应。

Treatment resistant non-catatonic mutism in schizophrenia responding to a combination of continuation electroconvulsive therapy and neuroleptics.

作者信息

Grover Sandeep, Dutt Alakananda, Chakrabarty Kaustav, Kumar Vineet

机构信息

Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Ind Psychiatry J. 2012 Jan;21(1):69-71. doi: 10.4103/0972-6748.110957.

Abstract

Non-catatonic mutism in schizophrenia has been described less frequently in literature. We describe the case of a young male who presented with non-catatonic mutism, secondary to first rank symptoms, which was refractory to adequate antipsychotic trials (quetiapine, risperidone, aripiprazole, ziprasidone, and trifluperazine) and responded to a combination of electroconvulsive therapy (ECT) and neuroleptics partially. However, when the ECT was continued in the continuation phase, the patient started speaking.

摘要

精神分裂症中的非紧张性缄默在文献中的描述较少。我们描述了一例年轻男性患者,其出现继发于一级症状的非紧张性缄默,对充分的抗精神病药物试验(喹硫平、利培酮、阿立哌唑、齐拉西酮和三氟拉嗪)无效,对电休克治疗(ECT)和抗精神病药物的联合治疗有部分反应。然而,在维持期继续进行ECT治疗时,患者开始说话。

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本文引用的文献

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Combined electroconvulsive-clozapine therapy.电休克合并氯氮平治疗
Clin Neuropharmacol. 2000 Jan-Feb;23(1):14-6. doi: 10.1097/00002826-200001000-00003.

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