Bio and Process Technology, VTT Technical Research Centre of Finland , P.O. Box 1000, FI-02044 VTT Espoo, Finland.
J Agric Food Chem. 2013 Jul 10;61(27):6754-62. doi: 10.1021/jf401738x. Epub 2013 Jun 26.
Lignin is a constituent of plant cell walls and thus is classified as part of dietary fiber. However, little is known about the role of lignin in gastrointestinal fermentation. In this work, a lignin-rich fraction was prepared from brewer's spent grain and subjected to an in vitro colon model to study its potential bioconversions and interactions with fecal microbiota. No suppression of microbial conversion by the fraction was observed in the colon model, as measured as short-chain fatty acid production. Furthermore, no inhibition on the growth was observed when the fraction was incubated with strains of lactobacilli and bifidobacteria. In fact, the lignin-rich fraction enabled bifidobacteria to survive longer than with glucose. Several transiently appearing phenolic compounds, very likely originating from lignin, were observed during the fermentation. This would indicate that the gut microbiota was able to partially degrade lignin and metabolize the released compounds.
木质素是植物细胞壁的组成部分，因此被归类为膳食纤维的一部分。然而，人们对木质素在胃肠道发酵中的作用知之甚少。在这项工作中，从啤酒糟中提取了富含木质素的部分，并在体外结肠模型中进行了研究，以研究其潜在的生物转化及其与粪便微生物群的相互作用。在结肠模型中，没有观察到该部分对微生物转化的抑制作用，如短链脂肪酸的产生所测量的那样。此外，当该部分与乳杆菌和双歧杆菌菌株孵育时，没有观察到对生长的抑制。事实上，富含木质素的部分使双歧杆菌的存活时间比葡萄糖更长。在发酵过程中观察到几种短暂出现的酚类化合物，很可能来自木质素。这表明肠道微生物群能够部分降解木质素并代谢释放的化合物。
