Research Chair on Laser Diagnosis of Cancers, King Saud University, Riyadh, Saudi Arabia.
Photodiagnosis Photodyn Ther. 2013 May;10(2):168-72. doi: 10.1016/j.pdpdt.2012.12.002. Epub 2013 Jan 15.
Gleason score is the most common method of grading the virulence of prostate malignancy and is based on the pathological assessment of morphology of cellular matrix. Since this involves the excision of the tissue, we are working on a new, minimally invasive, non-contact, procedure of spectral diagnosis of prostate malignancy. In this preliminary in vitro study reported here, we have analyzed 27 tissue samples (normal control=7: benign=8: malignant=12) by Stokes' shift spectra (SSS) to establish a one-to-one correspondence between spectral grading and Gleason grading.
格里森评分是评估前列腺癌恶性程度最常用的方法,其基础是对细胞基质形态学的病理评估。由于这种方法需要切除组织,因此我们正在研究一种新的、微创的、非接触式的前列腺癌光谱诊断方法。在本研究中,我们对 27 个组织样本(正常对照=7,良性=8,恶性=12)进行了斯托克斯位移光谱(SSS)分析,以建立光谱分级与格里森分级之间的一一对应关系。