KSU Research Chair for Laser Diagnosis of Cancer, King Saud University, Riyadh, Saudi Arabia.
Photochem Photobiol. 2011 Jan-Feb;87(1):208-14. doi: 10.1111/j.1751-1097.2010.00825.x. Epub 2010 Nov 19.
In this preliminary report, benign (n=8) and malignant (n=5) prostate tissues, in vitro, have been taken through autofluorescence spectroscopy. Employing Stokes' shift spectra and fluorescence emission spectra as tools of analysis, we were able to discriminate the two sets of tissues with sensitivity and specificity in excess of 85%. When the excised prostate chips were scanned with a spatial resolution of 1 mm, the epicenter of malignancy also could be delineated.
在这份初步报告中,我们对良性(n=8)和恶性(n=5)前列腺组织进行了离体荧光光谱分析。采用斯托克斯位移光谱和荧光发射光谱作为分析工具,我们能够以超过 85%的灵敏度和特异性区分这两组组织。当使用空间分辨率为 1 毫米的方法对切除的前列腺芯片进行扫描时,也能够描绘出恶性肿瘤的中心位置。