[MAGE基因在人肺癌中的表达及意义]
[Expression and significance of MAGE genes in human lung cancer].
作者信息
Li Guangxu, Song Pingping, Zhang Baijiang
机构信息
Shandong Academy of Medical Sciences, School of Medicine and Life Sciences, University of Jinan, Jinan 250022, China.
出版信息
Zhongguo Fei Ai Za Zhi. 2013 Jun;16(6):308-13. doi: 10.3779/j.issn.1009-3419.2013.06.07.
Abstract
Lung cancer is one of the common malignancies with an extremely poor prognosis, because of the current diagnostic techniques are not easy to find micrometastases. Melanoma associated antigens genes (MAGE) are tumor specific antigen genes, closely related to the occurrence, development and prognosis of lung cancer. The research of MAGE genes provide a new direction for the diagnosis and treatment of lung cancer.
摘要
肺癌是常见的恶性肿瘤之一，预后极差，因为目前的诊断技术不易发现微转移。黑色素瘤相关抗原基因（MAGE）是肿瘤特异性抗原基因，与肺癌的发生、发展及预后密切相关。对MAGE基因的研究为肺癌的诊断和治疗提供了新方向。
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