Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT.
Am J Obstet Gynecol. 2013 Nov;209(5):490.e1-9. doi: 10.1016/j.ajog.2013.06.018. Epub 2013 Jun 13.
Our objective was to estimate the occurrence of surgical site infections (SSI) after hysterectomy and the associated risk factors.
We conducted a cross-sectional analysis of the 2005-2009 American College of Surgeons National Surgical Quality Improvement Program participant use data files to analyze hysterectomies. Different routes of hysterectomy were compared. The primary outcome was to identify the occurrence of 30-day superficial SSI (cellulitis) after hysterectomy. Secondary outcomes were the occurrence of deep and organ-space SSI after hysterectomy. Logistic regression models were conducted to further explore the associations of risks factors with SSI after hysterectomy.
A total of 13,822 women were included in our final analysis. The occurrence of postoperative cellulitis after hysterectomy was 1.6% (n = 221 women). Risk factors that were associated with cellulitis were route of hysterectomy with an adjusted odds ratio (AOR) of 3.74 (95% confidence interval [CI], 2.26-6.22) for laparotomy compared with the vaginal approach, operative time >75th percentile (AOR, 1.84; 95% CI, 1.40-2.44), American Society of Anesthesia class ≥ 3 (AOR, 1.79; 95% CI, 1.31-2.43), body mass index ≥40 kg/m(2) (AOR, 2.65; 95% CI, 1.85-3.80), and diabetes mellitus (AOR, 1.54; 95% CI, 1.06-2.24) The occurrence of deep and organ-space SSI was 1.1% (n = 154 women) after hysterectomy.
Our finding of the decreased occurrence of superficial SSI after the vaginal approach for hysterectomy reaffirms the role for vaginal hysterectomy as the route of choice for hysterectomy.
本研究旨在评估子宫切除术术后手术部位感染(SSI)的发生情况及其相关危险因素。
我们对 2005-2009 年美国外科医师学会全国手术质量改进计划参与者使用数据文件进行了横断面分析,以分析子宫切除术。比较了不同的子宫切除术途径。主要结局是确定子宫切除术后 30 天内发生浅表 SSI(蜂窝织炎)的情况。次要结局是子宫切除术后深部和器官间隙 SSI 的发生情况。进行逻辑回归模型进一步探讨了子宫切除术后 SSI 与危险因素的关联。
共有 13822 名女性纳入最终分析。子宫切除术后发生术后蜂窝织炎的比例为 1.6%(n=221 名女性)。与阴道入路相比,与蜂窝织炎相关的危险因素包括子宫切除术途径(剖腹手术的调整优势比 [AOR]为 3.74 [95%置信区间 [CI],2.26-6.22])、手术时间超过第 75 百分位(AOR,1.84;95%CI,1.40-2.44)、美国麻醉医师学会分级≥3 级(AOR,1.79;95%CI,1.31-2.43)、体重指数≥40kg/m2(AOR,2.65;95%CI,1.85-3.80)和糖尿病(AOR,1.54;95%CI,1.06-2.24)。子宫切除术后深部和器官间隙 SSI 的发生率为 1.1%(n=154 名女性)。
本研究发现阴道入路子宫切除术术后浅表 SSI 的发生率降低,再次证实了阴道子宫切除术作为子宫切除术首选途径的作用。