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慢性腹泻的临床处理方法与管理

Clinical approach and management of chronic diarrhea.

作者信息

Abdullah Murdani, Firmansyah M Adi

机构信息

Department of Internal Medicine, Faculty of Medicine University of Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

出版信息

Acta Med Indones. 2013 Apr;45(2):157-65.

PMID:23770798
Abstract

Chronic diarrhea is defined as the passage of loose stools that last for more than 4 weeks. Although generally it is estimated that the prevalence of chronic diarrhea only ranges 3-5% of population, but it poses some specific equally essential challenges compared to acute diarrhea because there are many differential diagnosis that should be considered as the cause of chronic diarrhea. One of them includes colorectal cancer and the small intestinal bacterial overgrowth, known as SIBO. In general, chronic diarrhea can be categorized into watery, malabsorption, and inflammatory diarrhea. A proper history taking, physical examination and laboratory investigation is therefore necessary for clinician in managing chronic diarrhea. Overall, the management of chronic diarrhea includes two types, i.e. supportive and pharmacological management both for infectious and non-infectious etiologies. Pharmacological treatment can also be classified into two kinds of treatment including symptomatic and causal treatment, which can be achieved through empirical therapy.

摘要

慢性腹泻的定义为持续超过4周的稀便。虽然一般估计慢性腹泻的患病率仅占人口的3%-5%,但与急性腹泻相比,它带来了一些同样重要的特殊挑战,因为有许多鉴别诊断应被视为慢性腹泻的病因。其中包括结直肠癌和小肠细菌过度生长,即小肠细菌过度生长(SIBO)。一般来说,慢性腹泻可分为水样腹泻、吸收不良性腹泻和炎性腹泻。因此,临床医生在处理慢性腹泻时,进行适当的病史采集、体格检查和实验室检查是必要的。总体而言,慢性腹泻的管理包括两种类型,即针对感染性和非感染性病因的支持性管理和药物管理。药物治疗也可分为两种,包括对症治疗和病因治疗,这可以通过经验性治疗来实现。

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