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[类鼻疽病原体的超微结构特征及其在体内与吞噬细胞的相互作用]

[The ultrastructural characteristics of the causative agent of melioidosis and its interaction with phagocytes in vivo].

作者信息

Popov S F, Mel'nikov B I, Kurilov V Ia, Bozhko V G

出版信息

Mikrobiol Zh (1978). 1990 Mar-Apr;52(2):18-22.

PMID:2377083
Abstract

The electron microscopic studies have established that the virulent strain of Pseudomonas pseudomallei C-141, an agent of melioidosis, being intraperitoneally administered to guinea pigs, forms in vivo three morphological variants. One variant is capsule-free, while two others have a capsule which in the second variant may be referred by its characters to the microcapsule and in the third one to the macrocapsule. It has been shown that under the interaction of these three morphological variants with the microorganism cells the bacteria of the first and second variants are absorbed by phagocytes, whereas the microbial cells of the third morphological variant are more resistant to the phagocytosis.

摘要

电子显微镜研究证实,类鼻疽杆菌病病原体——类鼻疽假单胞菌C - 141的强毒株经腹腔注射给豚鼠后,在体内形成三种形态变体。一种变体无荚膜,另外两种有荚膜,其中第二种变体的荚膜根据其特征可归为微荚膜,第三种变体的荚膜可归为大荚膜。研究表明,在这三种形态变体与微生物细胞相互作用时,第一种和第二种变体的细菌被吞噬细胞吞噬,而第三种形态变体的微生物细胞对吞噬作用更具抗性。

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