利比亚班加西斋月禁食期间糖尿病酮症酸中毒的发病率
Incidence of Diabetic Ketoacidosis during Ramadan Fasting in Benghazi-Libya.
作者信息
Elmehdawi Rafik, Ehmida Mohammed, Elmagrehi Hanan
出版信息
Oman Med J. 2009 Apr;24(2):99-102. doi: 10.5001/omj.2009.23.
OBJECTIVES
Ramadan is the ninth month on the lunar calendar and it is a holy month for Muslims during which all healthy adults must fast from dawn to sunset. The risk of diabetic ketoacidosis is thought to be higher during Ramadan fasting due to insulin and glucagon alterations.
METHODS
A descriptive retrospective analysis of the records of all patients admitted with diabetic ketoacidosis to all Benghazi hospitals during the lunar year 1428 Hijri (2007-2008).
RESULTS
Fifteen episodes occurred during Ramadan compared to a mean of 19.45 episodes/month during the other lunar months (p<0.001), and there was no significant difference in the mean age (37.6±10 vs. 38.3±19, p=0.8), mortality rate (13.3% vs.14.4%, p=0.9) or in the length of hospitalization during Ramadan. The commonest precipitating factor for diabetic ketoacidosis during Ramadan was infection (46.6%) followed by miss dosing.
CONCLUSION
There was no increase in the incidence and mortality from DKA during Ramadan which might indicate that Ramadan fasting is not a significant risk factor for diabetic ketoacidosis.
目的
斋月是伊斯兰教历的第九个月，对穆斯林来说是神圣的月份，在此期间所有健康的成年人必须从黎明到日落禁食。由于胰岛素和胰高血糖素的变化，斋月禁食期间糖尿病酮症酸中毒的风险被认为更高。
方法
对回历1428年（2007 - 2008年）期间所有入住班加西医院的糖尿病酮症酸中毒患者的记录进行描述性回顾分析。
结果
斋月期间发生了15次发作，而其他农历月份的平均发作次数为每月19.45次（p<0.001），并且在平均年龄（37.6±10对38.3±19，p = 0.8）、死亡率（13.3%对14.4%，p = 0.9）或斋月期间的住院时间方面没有显著差异。斋月期间糖尿病酮症酸中毒最常见的诱发因素是感染（46.6%），其次是用药失误。
结论
斋月期间糖尿病酮症酸中毒的发病率和死亡率没有增加，这可能表明斋月禁食不是糖尿病酮症酸中毒的重要危险因素。
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